Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Prevalence and associated risk factors of work related musculoskeletal disorders among Building construction workers in Shire Endaslassiae town, Northern Ethiopia. [PDF]
Sci RepKinfe MG, Wami SD, Yenealem DG.
europepmc +1 more source
Tuning of data augmentation hyperparameters in deep learning to building construction image classification with small datasets. [PDF]
Int J Mach Learn Cybern, 2023 Ottoni ALC +3 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Building construction crack detection with BCCD YOLO enhanced feature fusion and attention mechanisms. [PDF]
Sci RepRen W, Zhong Z.
europepmc +1 more source
Occupational Skin Diseases among Building Construction Workers in Dar es Salaam, Tanzania. [PDF]
Ann Glob Health, 2021 Esmail RY, Sakwari GH.
europepmc +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Application of a Gyroid Structure for Thermal Insulation in Building Construction. [PDF]
Materials (Basel)Anwajler B, Szołomicki J, Noszczyk P.
europepmc +1 more source
Governmental Investments in Hospital Infrastructure Among Regions and Its Efficiency in China: An Assessment of Building Construction. [PDF]
Front Public Health, 2021 Lan T, Chen T, Hu Y, Yang Y, Pan J.
europepmc +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source