Results 101 to 110 of about 3,095,943 (305)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The state of the art in e-business: A case study from the Chinese construction industry [PDF]

open access: yes, 2012
In the 21st century, e-business is seen as the new frontier. Currently e-business has been widely used in other industry and to some extent in global construction market, particularly in developed countries, such as UK, EU and USA.
Perera, Srinath   +3 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

GS&E journal > Study on the optical quality and strength of glass edges after the grinding and polishing process

open access: yesChallenging Glass Conference Proceedings, 2020
Glass edges result from cutting glass sheets and a further optional finishing. The mechanical interference into the brittle material glass causes flaws and cracks at the edge surface.
Paulina Bukieda   +3 more
doaj  

Impact of Cutting Process Parameters on the Mechanical Quality of Processed Glass Edges

open access: yesChallenging Glass Conference Proceedings, 2022
The inspection of glass edges is gaining in importance in research, as the strength of a glass edge has been found to be highly dependent on its processing. Glass edges are produced by cutting.
Paulina Bukieda, Bernhard Weller
doaj  

Mission Impracticable: The Impossibility of Commercial Impracticability [PDF]

open access: yes, 2015
[Excerpt] “Residents of Chicago’s Streeterville neighborhood certainly cannot forget the recent financial crisis thanks to a gaping hole in their midst.
Camero, Jennifer
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Use of waste optical disc in concrete to promote Sustainable development in construction industry [PDF]

open access: yes, 2018
In recent years, happening of few catastrophic natural disasters have raise the awareness of public on environmental issue that the Earth is getting sick.
Adnan, Suraya Hani   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Evaluating Resilience and Thermal Comfort in Mediterranean Dwellings: A Level(s) Framework Approach

open access: yesApplied Sciences
The construction sector plays a pivotal role in urban development, providing a critical opportunity to foster a cultural shift towards the regeneration of housing stock.
Carmen Díaz-López   +3 more
doaj   +1 more source

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