Results 121 to 130 of about 5,854,515 (296)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ohio State Office Building under construction

open access: yes, 1931
Photograph of the partially-covered steel frame of the State Office (Ohio Departments of State) building, Columbus, ca. 1931-1932. Groundbreaking for the Ohio State Office Building took place on November 19, 1929.

core  

Assessing the impact of amended building regulations on the operations of UK construction companies [PDF]

open access: yes, 2008
The UK government continues to make regular amendments to building regulations. This is in order to keep these regulations relevant to today’s prevailing construction environment. More recently, UK building regulations have been amended to facilitate the
Ojiako, Udechukwu   +2 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Building construction illustrated / Francis D.K. Ching.

open access: yes, 2014
engineering bookfair2015Includes bibliographical references and index.1 volume (various pagings) :"This new edition of the revered classic remains as relevant as ever, providing the latest information in Francis D.K. Ching's signature style. Its rich and
Ching, Francis D. K., 1943-
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Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Construction workers on steel frame of State Office Building

open access: yes, 1931
Photograph of construction workers on the steel frame of the State Office (Ohio Departments of State) building in Columbus, ca. 1931-1932. Groundbreaking for the Ohio State Office Building took place on November 19, 1929.

core  

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