Results 121 to 130 of about 602,519 (297)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Futuristic construction communication infrastructures : secure and safe with no wires [PDF]

open access: yes, 2009
Wireless technology is already available and used in several industrial sectors. In the next few years it is envisaged that the technology will mature and converge with other technologies providing the ability to communicate and exchange data and ...
Stephenson, Paul, Strachan, Rebecca
core  

Glass Edges in the Building Industry

open access: yesChallenging Glass Conference Proceedings
In the building industry, different types of glass edges are used depending on their application and function. A widespread assumption is that the edge strength increases with the degree of optical finishing.
Paulina Bukieda   +3 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Construction Site [PDF]

open access: yes, 1948
New construction by Bowers Building and Construction Company at the site of the old Mission Cigar store, 129 South Main ...
Shipler Commercial Photographers; Shipler, Harry
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Lean construction: Prospects for the German construction industry [PDF]

open access: yes, 2007
There is little, if any, information available about the range and dissemination of lean concepts among construction companies in Germany. Building on the methodologies and conceptual frameworks used in earlier work in the UK (Common et al., 2000) and ...
Walter, Lorenz, Johansen, Eric
core  

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