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Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Feature assessment in data-driven models for unlocking building energy flexibility
Data-driven approaches are playing an increased role in building automation. This can, in part, be attributed to building operation and energy management system data becoming more readily accessible. A particular application is models to allow predictive
Donal P. Finn +3 more
core +1 more source
Managing data of sensor-equipped transportation networks using graph databases [PDF]
In this paper, we are concerned with data pertinent to transportation networks, which model situations in which objects move along a graph-like structure.
E. Bollen +3 more
doaj +1 more source
Weather data Schiphol 2009-2018 and energy demand for a case study building.
This document contains the description of the dataset ‘weather data Schiphol 2009-2018 and energy demand for a case study building’ and a description of the input parameters used to create the data.
van der Spoel, W.H. (Willem) +3 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Standards for Data Space Building Blocks
Data spaces are conceptualised as a trusted and secure distributed data ecosystem through which to exchange resources in the Web. Several efforts define guidance toward data space implementation, such as reference architectures and frameworks. As yet, the proposed data space solutions do not provide common and mature implementation options yet, and ...
Francesca Noardo +7 more
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
DeepScratch: Single-cell based topological metrics of scratch wound assays
Changes in tissue architecture and multicellular organisation contribute to many diseases, including cancer and cardiovascular diseases. Scratch wound assay is a commonly used tool that assesses cells’ migratory ability based on the area of a wound they ...
Avelino Javer +2 more
doaj +1 more source
Building a Data Warehouse step by step [PDF]
Data warehouses have been developed to answer the increasing demands of quality information required by the top managers and economic analysts of organizations. Their importance in now a day business area is unanimous recognized, being the foundation for
Gheorghe MATEI, Manole VELICANU
core
District data management, modelling and visualization via interoperability [PDF]
Data management has been one of the most interesting research fields within the smart city framework over the last years, with the aim of optimizing energy saving at district level.
Marchi, Francesca +8 more
core +1 more source

