Results 121 to 130 of about 1,597,081 (316)

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

The EBRAINS Hodgkin-Huxley Neuron Builder: An online resource for building data-driven neuron models. [PDF]

Front Neuroinform, 2022
Bologna LL, Smiriglia R, Lupascu CA, Appukuttan S, Davison AP, Ivaska G, Courcol JD, Migliore M.   +7 more
europepmc   +1 more source

Simulation support for performance assessment of building components

, 2008
The determination of performance metrics for novel building components requires that the tests are conducted in the outdoor environment. It is usually difficult to do this when the components are located in a full-scale building because of the difficulty
Strachan, P.A.
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Bayesian predictive system for assessing the damage intensity of residential masonry buildings under the impact of continuous ground deformation

Scientific Reports
The paper introduces a method for predicting damage intensity in masonry residential buildings situated in mining areas, focusing on the impact of large-scale continuous ground deformation.
Janusz Rusek, Leszek Chomacki, Leszek Słowik   +2 more
doaj   +1 more source

A Roadmap for Building Data Science Capacity for Health Discovery and Innovation in Africa. [PDF]

Front Public Health, 2021
Beyene J, Harrar SW, Altaye M, Astatkie T, Awoke T, Shkedy Z, Mersha TB.   +6 more
europepmc   +1 more source

Haltwhistle War Memorial Hospital Archaeological Building Recording (OASIS ID gbbuildi1-129159)

, 2013
A planning application has been submitted for the demolition of the existing war memorial hospital and associated buildings owing to the construction of an integrated health and social care facility, Haltwhistle War Memorial Hospital, Westgate ...
GB Building Solutions
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

BIM-SeL: Building Information Modelling Data-Adaptive Natural-Language Sequence Labeling Using Machine Learning

Buildings
Building Information Modelling has become a common paradigm in the construction industry. To bridge the gap between end users and BIM data, some studies have adopted Natural Language Processing (NLP) in the BIM applications.
Qi Qiu, Xiaoping Zhou, Yukang Wang, Jichao Zhao, Maozu Guo, Xin Zhang   +5 more
doaj   +1 more source