Results 131 to 140 of about 1,597,081 (316)

Cityscape LoRa Signal Propagation Predicted and Tested Using Real-World Building-Data Based O-FDTD Simulations and Experimental Characterization. [PDF]

Sensors (Basel), 2021
Adão RMR, Balvís E, Carpentier AV, Michinel H, Nieder JB.   +4 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Iterative Application of UMAP-Based Algorithms for Fully Synthetic Healthcare Tabular Data Generation

Algorithms
Building on a previously developed partially synthetic data generation algorithm utilizing data visualization techniques, this study extends the novel algorithm to generate fully synthetic tabular healthcare data.
Carla Lázaro, Cecilio Angulo
doaj   +1 more source

Facing the growing problem of the electric power consumption in Egyptian residential building using building performance simulation program

, 2013
Egypt has been experiencing recurrent power cuts especially at the summer, with the problem being made worse by the extra demands placed on the electrical grid by the advent of the holy month of Ramadan.
Tuohy, Paul Gerard, Elharidi, Aly Mohamed Aly Hassan, Teamah, M.   +2 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Using UMAP for Partially Synthetic Healthcare Tabular Data Generation and Validation

Sensors
In healthcare, vast amounts of data are increasingly collected through sensors for smart health applications and patient monitoring or diagnosis. However, such medical data often comprise sensitive patient information, posing challenges regarding data ...
Carla Lázaro, Cecilio Angulo
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Impact of building envelope design on energy consumption of the Auckland library

, 2017
This pilot study is to investigate impact of building envelope design on energy consumption of Auckland public libraries. There are about 55 public libraries in Auckland.
Su, Bin
core  

Data-driven Building Metadata Inference

, 2018
Building technology has been developed due to the improvement of information technology. Specifically, a human can control and monitor the building operation by a number of sensors and actuators.
June Young Park (5047475)
core   +1 more source