Results 41 to 50 of about 193,765 (281)

Dynamic B-SIM application for energy consumption estimation of DOAS with FCU HVAC system during design phase [PDF]

open access: yesE3S Web of Conferences, 2019
The investigation presents a strategic approach during the design process using advanced energy performance simulation technology. Team coordination and building performance efficiency during the design process is aided by conducting a performance based ...
Harmathy Norbert
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Building Energy Simulation and Monitoring: A Review of Graphical Data Representation

open access: yesEnergies, 2022
Data visualization has become relevant in the framework of the evolution of big data analysis. Being able to understand data collected in a dynamic, interactive, and personalized way allows for better decisions to be made when optimizing and improving ...
Ofelia Vera-Piazzini   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Building energy performance assessment for existing commercial buildings with heritage values [PDF]

open access: yesMATEC Web of Conferences, 2019
The building sector accounts for 19% of Australia's energy consumption and around 23% of the greenhouse gas emissions. In 2005, commercial buildings in Australia were responsible for 10% or 26 megatonnes (Mt) of the nation's greenhouse gas emissions ...
Wong James Pow Chew
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Comparison of a Solar Driven Absorption Chiller and Photovoltaic Compression Chiller Under Different Demand Profiles: Technological, Environmental and Economic Performance

open access: yesEnergies
HVAC systems are becoming increasingly important around the world due to the increasing need for climatization in recent years. While district heating systems have been used for a long time, district cooling systems tend to be something that is only ...
Juan José Roncal-Casano   +4 more
doaj   +1 more source

From the energy performance certificate to the building renovation passport [PDF]

open access: gold, 2021
Manuela Grecchi   +3 more
openalex   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

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