Results 61 to 70 of about 189,008 (233)

Analysis of Accuracy Determination of the Seasonal Heat Demand in Buildings Based on Short Measurement Periods

Energies, 2018
In this paper, we present a multi-variant analysis of the determination of the accuracy of the seasonal heat demand in buildings. The research was based on the linear regression method for data obtained during short periods of measurement.
Joanna Ferdyn-Grygierek, Dorota Bartosz, Aleksandra Specjał, Krzysztof Grygierek   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Simulation and the building performance gap

Buildings & Cities
Highlights This special collection examines simulation and the building performance gap. It focuses on quality assurance measures, case studies, user studies that address the development of trust in the performance calculations of designers.
Michael Donn
doaj   +1 more source

Sacrificial Template Synthesis of Copper Tungstate: Influence of Preparing Conditions on Morphology and Photoactivity

International Journal of Electrochemical Science, 2019
Morphology-controlled synthesis of ternary transition metal oxides is very important for their application in many fields. As a typical n-type semiconductor ternary oxide, CuWO4 finds application in solar water splitting as a photoanode material. In this
Ben Peng, Chao Li, Changsheng Yue, Peng Diao   +3 more
doaj   +1 more source

The role of double-skin facade configurations in optimizing building energy performance in Erbil city. [PDF]

Sci Rep, 2023
Naddaf MS, Baper SY.
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Zone-wise occupancy schedules developed using Time Use Survey data for building energy performance simulations. [PDF]

Data Brief, 2023
Sood D, Alhindawi I, Ali U, Finn D, McGrath JA, Byrne MA, O'Donnell J.   +6 more
europepmc   +1 more source