Results 81 to 90 of about 1,732,185 (284)
Heating, Ventilation and Air Conditioning (HVAC) consumes a significant fraction of energy in commercial buildings. Hence, the use of optimization techniques to reduce HVAC energy consumption has been widely studied. Model predictive control (MPC) is one
Jain, Milan +3 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Improving Building Energy Efficiency through Measurement of Building Physics Properties Using Dynamic Heating Tests [PDF]
© 2019 the author. Licensee MDPI, Basel, Switzerland.Buildings contribute to nearly 30% of global carbon dioxide emissions, making a significant impact on climate change. Despite advanced design methods, such as those based on dynamic simulation tools, a
Jankovic, Ljubomir
core +3 more sources
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Building in Historical Areas: Identity Values and Energy Performance of Innovative Massive Stone Envelopes with Reference to Traditional Building Solutions [PDF]
The intrinsic nature of local rocks shaped the features of built heritage in historical centers. The resulting building culture is part of the cultural heritage itself, and must be considered when building in such areas, while it is essential to solve ...
Ferrero, Marco +2 more
core +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
In this paper, we present a multi-variant analysis of the determination of the accuracy of the seasonal heat demand in buildings. The research was based on the linear regression method for data obtained during short periods of measurement.
Joanna Ferdyn-Grygierek +3 more
doaj +1 more source
Building Appliances Energy Performance Assessment [PDF]
Jasiunas, Zygimantas +2 more
openaire +1 more source
How to achieve sustainability : regulatory challenges [PDF]
The importance of designing sustainable buildings is gaining greater acceptance worldwide. Evidence of this is how regulators are incorporating sustainable design principles into building regulations and requirements.
Ambrose, Michael, Miller, Anne
core +1 more source

