Results 51 to 60 of about 166,272 (305)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Climate data for hygrothermal simulations of Brussels

Data in Brief, 2022
Moisture is a dominant agent in the degradation of building components. To assess degradation phenomena in building envelopes, hygrothermal simulations are performed.
Isabeau Vandemeulebroucke, Steven Caluwaerts, Nathan Van Den Bossche   +2 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Optimization for energy efficiency of underground building envelope thermal performance in different climate zones of China

E3S Web of Conferences, 2017
The object of this article is to investigate the influence of thermal performance of envelopes in shallow-buried buildings on energy consumption for different climate zones of China.
Shi Luyang, Liu Jing, Zhang Huibo
doaj   +1 more source

An Explicit Finite Element Method for Thermal Simulations of Buildings with Phase Change Materials

Energies, 2021
The thermal performance of building envelopes is essential for building thermal comfort and the reduction of building energy requirements. Phase change materials (PCMs) implemented in building envelopes can improve thermal performance. An explicit finite
Hongxia Zhou, Åke Fransson, Thomas Olofsson   +2 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Inter-Building Effect and Its Relation with Highly Reflective Envelopes on Building Energy Use: Case Study for Cities of Japan

Atmosphere, 2017
The built environment with respect to building envelope designs and the surrounding micro-environment significantly affects building energy use. The influence of the inter-building effect (IBE) on building energy use cannot be ignored and thermal ...
Jihui Yuan, Craig Farnham, Kazuo Emura
doaj   +1 more source

A Byzantine Fault-Tolerant Ordering Service for the Hyperledger Fabric Blockchain Platform [PDF]

, 2017
Hyperledger Fabric (HLF) is a flexible permissioned blockchain platform designed for business applications beyond the basic digital coin addressed by Bitcoin and other existing networks.
Bessani, Alysson, Sousa, João, Vukolić, Marko   +2 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Experimental and numerical assessment of breathing walls performance for theimprovement of air quality and comfort indoors

Tema, 2016
The construction of airtight building envelopes within nearly Zero Energy Buildings is likely to generate thermo-hygrometric discomfort indoors, that needs to be managed with airconditioning and ventilation systems.
Elisa Di Giuseppe, Marco D’Orazio
doaj   +1 more source