Results 131 to 140 of about 3,099,998 (314)
BIM-Based Machine Learning Application for Parametric Assessment of Building Energy Performance
EnergiesThe energy performance of buildings has become a main concern globally in response to increased energy demand, the environmental impacts of energy production, and the reality of energy poverty.
Panagiotis Tsikas +3 more
doaj +1 more source
Building-Information-Modeling Based Approach to Simulate Strategic Location of Shelter in Place and Its Strengthening Method. [PDF]
Materials (Basel), 2021 Kim YH, Choi JS, Yuan TF, Yoon YS.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Integrating Building Management Systems in High-Rise Structures using Building Information Modeling
Proceedings of the International Conference of Contemporary Affairs in Architecture and Urbanism-ICCAUARapid industrialization and population growth in urban areas has resulted in scarce land resources thus changing built form tremendously. Complex construction such as high-rise structures are becoming an essential requirement in urban areas.
Purva Mujumdar, Shlok Agarwal
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Applications of Building Information Modelling in the Operation and Maintenance Phase of Construction Projects: A Framework for the Malaysian Construction Industry [PDF]
, 2023 Muhammad Ali Musarat +5 more
openalex +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source