Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Building Information Modeling Learning Behavior of AEC Undergraduate Students in China. [PDF]
Behav Sci (Basel), 2022 Peng P +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Building Information Modeling BIM - Level of Digital Construction
Archives of Civil Engineering, 2017 In the paper the topic of Building Information Technology BIM is investigated. It is new in Polish circumstances technology for construction and for building product industry, which contribute to change and develop level of industrialization.
Glema A.
doaj +1 more source
Prototyping a Chatbot for Site Managers Using Building Information Modeling (BIM) and Natural Language Understanding (NLU) Techniques. [PDF]
Sensors (Basel), 2023 Lin WY.
europepmc +1 more source
Micro-bias and macro-performance
, 2008 We use agent-based modeling to investigate the effect of conservatism and partisanship on the efficiency with which large populations solve the density classification task--a paradigmatic problem for information aggregation and consensus building.
Amaral, L. A. N. +5 more
core +2 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Considering the Feasibility of Semantic Model Design in the Built-Environment
Buildings, 2014 Building Information Modeling (BIM) is the process of structuring, capturing, creating, and managing a digital representation of physical and/or functional characteristics of a built space [1].
Hubert Grzybek +3 more
doaj +1 more source
Building Information Modeling (BIM) Driven Carbon Emission Reduction Research: A 14-Year Bibliometric Analysis. [PDF]
Int J Environ Res Public Health, 2022 Liu Z, Li P, Wang F, Osmani M, Demian P.
europepmc +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source