Results 61 to 70 of about 902,578 (275)

Problem-based learning: enhancing students learning of building information modelling [PDF]

open access: yes, 2018
Building Information Modelling (BIM) is an innovative collaborative process underpinned by digital technologies introduced to improve project performance in the Architecture, Engineering and Construction (AEC) industry.
Chukwudi, Obi   +2 more
core  

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack   +39 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Digital Engineering: a Case Study in an Irish Consultancy Practice

open access: yesJournal of Sustainable Design and Applied Research in Innovative Engineering of the Built Environment, 2019
The building services engineering (BSE) industry has wrestled with its productivity gap for many years and the time has come to embrace innovation. Its practitioners now have the key to unlock the future by the smart use of technology, which has the ...
Raymond Reilly
doaj   +1 more source

Overview of building information modelling in healthcare projects [PDF]

open access: yes, 2011
In this paper, we explore how BIM functionalities together with novel management concepts and methods have been utilized in thirteen hospital projects in the United States and the United Kingdom. Secondary data collection and analysis were used as the
Dave, B   +4 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Development of a building information modelling (BIM) migration path model for construction professionals [PDF]

open access: yes, 2018
The construction professionals have the notion that by implementing Building Information Modelling (BIM) in construction could overcome problems such as delay, cost overrun, clashes in project design and undesirable quality in construction.
Brahim, Juliana
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Building information modelling to cut disruption in housing retrofit [PDF]

open access: yes, 2016
There is a large stock of solid-wall homes in the UK with poor thermal insulation and low energy performance. Although the UK government has supported efforts to improve these buildings, the identification of appropriate technical solutions that ...
Alsaadi AN   +24 more
core   +1 more source

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