Results 81 to 90 of about 100,537 (296)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Building Information Modelling for Visualisation in AEC Education

open access: yes, 2005
This paper outlines the process used to introduce building information modelling into the academic curriculum of built environment students and reflects on the techniques used to ensure appropriate use of parametric tools for the purposes of ...
M. Johansson, M. Roupé, M. Horne
core  

1º Congresso Português de Building Information Modelling [PDF]

open access: yes, 2016
[Excerto] Prefácio: A crescente importância da representação digital de elementos de construção, tornada possível pelas metodologias ‘Building Information Modelling’ (BIM), está a introduzir alterações muito relevantes no projeto, na construção e gestão ...
Granja, José   +9 more
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Building Information Modelling of Modern Historic Buildings

open access: yes, 2007
This paper reports a research study which evaluated the possibilities of building information modelling (BIM) within renovation of buildings of significant architectural, historic or cultural values.
M. Rajala, S. Freese, H. Penttila
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Building Information Modelling: Present realities and Future possibilities

open access: yesInternational Journal of Engineering and Management Sciences, 2018
BIM (Building Information Modelling), a term that is drawing the attention worldwide in the construction industry and governments, is a complex concept that involves management effort, tools and applications for enhancing information flow and therefore ...
Sergey Pogorelskiy, Diego Alava
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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