Results 61 to 70 of about 100,537 (296)

5D Building Information Modelling – A Practicability Review

open access: yesMATEC Web of Conferences, 2016
Quality, time and cost are the three most important elements in any construction project. Building information that comes timely and accurately in multiple dimensions will facilitate a refined decision making process which can improve the construction ...
Lee Xia Sheng   +2 more
doaj   +1 more source

Green BIM Concept – Scandinavian Inspirations

open access: yesArchives of Civil Engineering, 2016
This article discusses an integrated concept of sustainable building and of Building Information Modelling (BIM) by means of implementation of the Green BIM management method.
Araszkiewicz K.
doaj   +1 more source

Towards an Interoperable Approach for Modelling and Managing Smart Building Data: The Case of the CESI Smart Building Demonstrator

open access: yesBuildings, 2022
Buildings have a significant impact on energy consumption and carbon emissions. Smart buildings are deemed to play a crucial role in improving the energy performance of buildings and cities.
Omar Doukari   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Building Information Modelling design ecologies - a new model? [PDF]

open access: yes, 2012
This paper considers the barriers to BIM adoption and demonstrates they are symptoms of existing problems in the Architecture, Engineering, Construction, and Operations (AECO) industry. When current external pressures are considered, a varied and complex
Jones, Derek, Dewberry, Emma
core   +1 more source

Building Information Modelling, Artificial Intelligence and Construction Tech

open access: yesDevelopments in the Built Environment, 2020
Adoption of digital information tools in the construction sector provides fertile ground for the birth and growth of companies that specialize in applications of technologies to design and construction.
Rafael Sacks, PhD   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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