Results 71 to 80 of about 19,365,633 (281)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Building Information Modelling of Modern Historic Buildings
, 2007 This paper reports a research study which evaluated the possibilities of building information modelling (BIM) within renovation of buildings of significant architectural, historic or cultural values.
M. Rajala, S. Freese, H. Penttila
core
Automated compliance checking using building information models [PDF]
, 2010 Building designs in the UK are currently checked manually against a frequently changing and increasingly complex set of building regulations. This is a major task for both designers and enforcers, often leading to ambiguity, inconsistency in assessments ...
Greenwood, David +4 more
core
Construction work health and safety management using building information modelling
, 2021 The high rates of fatalities and injuries in the construction industry highlight the importance of work health and safety (WHS). Building information modelling (BIM) could significantly improve WHS management in construction, but integration has been ...
Angelica Vårhammar +15 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Building information modelling for FM using IFC [PDF]
, 2005 Facility managers have to acquire, integrate, edit and update diverse facility information ranging from building elements & fabric data, operational costs, contract types, room allocation, logistics, maintenance, etc.
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Building Information Modelling: Present realities and Future possibilities
International Journal of Engineering and Management Sciences, 2018 BIM (Building Information Modelling), a term that is drawing the attention worldwide in the construction industry and governments, is a complex concept that involves management effort, tools and applications for enhancing information flow and therefore ...
Sergey Pogorelskiy, Diego Alava
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Building Information Modelling (BIM) : insights from collaboration and legal perspectives
, 2022 World Building Congress 2022, 26-30 June 2022, Melbourne, Australia202212 bcvcVersion of ...
Lai, J, Wong, P
core +1 more source