Results 101 to 110 of about 100,537 (296)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Evolution + Bim: the Utilization of Building Information Modelling at an Early Design Stage
, 2008 The paper introduces an experimental design studio that explores the optimal use of current digital technologies in order to allow the adoption of Building Information Modelling at an early stage of the design process.
H.J. Park
core
Model interoperability in building information modelling [PDF]
, 2009 The exchange of design models in the design and construction industry is evolving away from 2-dimensional computer-aided design (CAD) and paper towards semantically-rich 3-dimensional digital models. This approach, known as Building Information Modelling
Steel, Jim, Drogemuller, Robin
core
Towards the cognitive building: information modeling for the energy audit
Tema, 2018 The new paradigm of smart building requires the accomplishment of occupants needs through the analysis of data gathered within the building, which switches from activities host to provider of customized services for occupants. The digitalization supports
Giuseppe Martino Di Giuda +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Automated compliance checking using building information models
, 2010 Building designs in the UK are currently checked manually against a frequently changing and increasingly complex set of building regulations. This is a major task for both designers and enforcers, often leading to ambiguity, inconsistency in assessments ...
Greenwood, David +4 more
core
A bibliometric analysis of building information modelling implementation barriers in the developing world using an interpretive structural modelling approach. [PDF]
Heliyon, 2023 Takyi-Annan GE, Zhang H.
europepmc +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2018 Building Information Modelling (BIM) and Discrete Event Simulation (DES) are tools widely used in the context of the construction industry. While BIM is used to represent the physical and functional characteristics of a facility, DES models are used to ...
Tizani, Walid +2 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source