Results 111 to 120 of about 907,023 (287)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Hybrid Revit and a new MCDM approach of energy effective nursing-home designed by natural stone and green insulation materials

Journal of Civil Engineering and Management
The requisition for maintainable constructions has been greatly raising over the last several years. To fulfil the maintainability necessities of a construction, decisions or changes must be done to a construction in the course of the preconstruction ...
Figen Balo, Alptekin Ulutaş, Željko Stević, Hazal Boydak, Edmundas Kazimieras Zavadskas   +4 more
doaj   +1 more source

Performance Predictions of Dry and Wet Vapors Ejectors Over Entire Operational Range

Energies, 2017
If a traditional ideal-gas ejector model is used to evaluate the performance of a wet vapor ejector, large deviations from the experimental results will be unavoidable.
Fenglei Li, Zhao Chang, Qi Tian, Changzhi Wu, Xiangyu Wang   +4 more
doaj   +1 more source

Monitoring and Assessment of Indoor Environmental Conditions in Educational Building Using Building Information Modelling Methodology. [PDF]

Int J Environ Res Public Health, 2022
Aguilar AJ, de la Hoz-Torres ML, Ruiz DP, Martínez-Aires MD.   +3 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Impacts of building information modelling (BIM) on communication network of the construction project: A social capital perspective. [PDF]

PLoS One, 2022
Huang Y, Wu L, Chen J, Lu H, Xiang J.
europepmc   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Generative Design in Building Information Modelling (BIM): Approaches and Requirements. [PDF]

Sensors (Basel), 2021
Ma W, Wang X, Wang J, Xiang X, Sun J.
europepmc   +1 more source

Building information modelling (BIM) implementation and remote construction projects: issues, challenges, and critiques. [PDF]

, 2012
The construction industry has been facing a paradigm shift to (i) increase productivity, efficiency, infrastructure value; quality and sustainability (ii) reduce lifecycle costs, lead times and duplications via effective collaboration and communication ...
Arayici, Y, Coates, SP, Egbu, CO
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source