Results 91 to 100 of about 3,800,881 (287)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The development of a generic systems-level model for combustion-based domestic cogeneration [PDF]

, 2008
The provision of heat and power to dwellings from micro-cogeneration systems is gaining credence around the developed world as a possible means to reduce the significant carbon emissions associated with the domestic sector. However, achieving the optimum
Ferguson, Alex, Griffith, Brent, Kelly, Nick, Weber, Andreas   +3 more
core  

Energy and technological refurbishment of the School of Architecture Valle Giulia, Rome [PDF]

, 2017
Modern architecture built in historical urban contexts represents a demanding issue when its energy efficiency should be improved. Indeed, the strongest efforts have to be made to maintain the architectural identity and its harmony with the surrounding ...
Clemente, C., De Santoli, L., Lucci, S., Mancini, F.   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Correlation Analysis of Building Performance and Occupant’s Satisfaction via Post Occupancy Evaluation for Malaysia’s Public Buildings [PDF]

The purpose of a building is to provide shelter for activities that carried out by the building users. The question is, does the facilities in the building perform well and appropriate to its use?
Adnan, Hamimah, Husin, Husrul Nizam, Khalil, Natasha, Nawawi, Abdul Hadi   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of reinforced concrete structural durability in the post-occupation phase - A case study in Novo Hamburgo/RS

REM: International Engineering Journal
Researches on building performance have been developed over time. The Brazilian Performance Standard - NBR 15575 - deals with the issues of durability applied to residential buildings, establishing criteria and parameters to classify the systems into ...
Guilherme Manfredini Bueno, Eduardo Rimolo Carneiro, Ana Claudia Lemos Ramão, Giulianna Ody Piva, Bernardo Fonseca Tutikian   +4 more
doaj   +1 more source

EPS Cement Sandwich Panel Walls: A Sustainable and Energy-Efficient Solution for Residential Buildings - A Simulation-Based Study of a Residential Villa in Cairo, Egypt [PDF]

JES: Journal of Engineering Sciences
The construction industry represents a considerable portion of global energy consumption and carbon emissions, necessitating the investigation of sustainable alternatives in building materials.
Eslam Moraekip
doaj   +1 more source

Building performance simulations can inform IoT privacy leaks in buildings. [PDF]

Sci Rep, 2023
Wang A, Campbell B, Heydarian A.
europepmc   +1 more source

A Scalable Deep Neural Network Architecture for Multi-Building and Multi-Floor Indoor Localization Based on Wi-Fi Fingerprinting

, 2017
One of the key technologies for future large-scale location-aware services covering a complex of multi-story buildings --- e.g., a big shopping mall and a university campus --- is a scalable indoor localization technique.
Huang, Kaizhu, Kim, Kyeong Soo, Lee, Sanghyuk   +2 more
core   +1 more source