Results 71 to 80 of about 754,439 (266)
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
In-use Energy Performance Study Of Automated Smart Homes
Journal of Sustainable Design and Applied Research in Innovative Engineering of the Built Environment, 2019 Domestic energy demand has been high on the carbon reduction agenda for some time. Today new homes are being designed following the “fabric first” principle which is reducing heat demand, but it is shifting the design challenge to ventilation.
J. MIles, K. A. Kelly, P. Sassi
doaj +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Biophilic Design and Climate Change: Performance Parameters for Health
Frontiers in Built Environment, 2019 Biophilic design is one of a number of trending design practices that rely on nature-based systems, engineering principles and design cues to improve environmental quality, health, and efficiency.
Julia Africa +3 more
doaj +1 more source
Computer simulation and measurements of a building with top-cooling [PDF]
, 2005 This paper deals with the use of computer simulations both for design support of a new building including its heating, ventilation and air-conditioning (HVAC) systems and for optimization of the HVAC control strategy during operation of the completed ...
Lain, M Milos +8 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Integration of control and building performance simulation software by run-time coupling
, 2003 This paper presents the background, approach and initial results of a project, which aims to achieve better integrated building and systems control modeling in building performance simulation by runtime coupling of distributed computer programs.
Soethout, L.L. +9 more
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