Results 61 to 70 of about 537,329 (247)
In-use Energy Performance Study Of Automated Smart Homes
Journal of Sustainable Design and Applied Research in Innovative Engineering of the Built Environment, 2019 Domestic energy demand has been high on the carbon reduction agenda for some time. Today new homes are being designed following the “fabric first” principle which is reducing heat demand, but it is shifting the design challenge to ventilation.
J. MIles, K. A. Kelly, P. Sassi
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biophilic Design and Climate Change: Performance Parameters for Health
Frontiers in Built Environment, 2019 Biophilic design is one of a number of trending design practices that rely on nature-based systems, engineering principles and design cues to improve environmental quality, health, and efficiency.
Julia Africa +3 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
AtmosphereEnergy retrofit interventions have become increasingly critical as building sectors worldwide pursue decarbonization targets and improved energy efficiency. However, establishing robust causal inference about retrofit impacts on indoor climate conditions
Asit Kumar Mishra
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Effective interdisciplinary stakeholder engagement in net zero building design
Buildings & CitiesStakeholder engagement is crucial to the design and construction stages of net zero buildings, requiring interdisciplinary collaboration to promote the integrated design process.
Simon Vakeva-Baird +3 more
doaj +1 more source
The Evaluation of Building’s Structural Reliability of Masjid Tuha Indrapuri, Aceh Besar
Elkawnie: Journal of Islamic Science and Technology, 2019 Masjid Tuha Indrapuri is one the ancient mosques in Aceh located in the district of Aceh Besar. The precise location of the mosque is in Indrapuri, Aceh Besar. Masjid Tuha Indrapuri exists right in the complex of the former temple.
Riza Aulia Putra, Saiful Hadi
doaj +1 more source