Results 51 to 60 of about 754,439 (266)
Direct Displacement Based Design and Capacity Spectrum Method for Special Moment Resisting Frame
Logic, 2020 In designing seismic-resistant buildings, it is commonly used Forced-Based Design method. The concept of the Force-Based Design (FBD) method is based on an elastic analysis of the structure and indirectly shows the performance level of the structure ...
Anis Rosyidah, Nadhila Ramadhani A.P.
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Estimating Occupancy Using Interactive Learning With a Sensor Environment: Real-Time Experiments
IEEE Access, 2019 Interactive learning plays a key role in extending the occupant behavior implementation toward smart buildings. Efficient feedbacks can be obtained from the end user by involving occupants and increasing their awareness about energy systems.
Manar Amayri +3 more
doaj +1 more source
On selecting weather data sets to estimate a building design's robustness to climate variations [PDF]
, 2009 The integration of techniques for uncertainty and sensitivity analysis in building performance simulation (BPS) has a number of potential benefits related to design.
Struck, C. +4 more
core
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The relation between building assessment systems and building performance simulation [PDF]
, 2006 The aim of the paper is to reveal the relationship between building performance simulation and building assessment systems as a performance indicator.
Ulukavak Harputlugil, G., Hensen, J.L.M.
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source