Results 111 to 120 of about 3,800,881 (287)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

BIPV: a real-time building performance study for a roof-integrated facility

International Journal of Sustainable Energy, 2018
Building integrated photovoltaic system (BIPV) is a photovoltaic (PV) integration that generates energy and serves as a building envelope. A building element (e.g.
Gayathri Aaditya, Monto Mani
doaj   +1 more source

The Potential for the Use of the Occupants’ Comments in the Analysis and Prediction of Building Performance

Buildings, 2012
The authors investigated the occupants’ perceptions of 47 commercial and institutional buildings worldwide. These investigations involved the personal distribution and collection of a questionnaire survey seeking the occupants' perceptions (scored ...
Clare Dykes, George Baird
doaj   +1 more source

Artificial Weathering Resistance Test Methods for Building Performance Assessment of Profiles Made of Natural Fibre-Reinforced Polymer Composites. [PDF]

Materials (Basel), 2021
Sudoł E, Kozikowska E, Szewczak E.
europepmc   +1 more source

Evaluation of a prescriptive ventilation standard with regard to 3 different performance indicators [PDF]

, 2009
In this paper, the performance of Belgian building code compliant residential ventilation systems is evaluated on multiple performance indicators: occupant exposure to bio-effluents, occupant exposure to other use-related pollutants (odours) and occupant
Janssens, Arnold, Laverge, Jelle
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Manchester Civil Justice Centre: Procuring and Managing an Institutional Building with a Mixed Mode Ventilation System—A Case for Post-Occupancy Evaluation

Buildings, 2013
Manchester Civil Justice Centre is a striking contemporary 14 storey court building which has won awards for many different aspects of its design, construction and sustainability.
John Napier
doaj   +1 more source

Effects of time reversal symmetry in dynamical decoupling

, 2011
Dynamical decoupling (DD) is a technique for preserving the coherence of quantum mechanical states in the presence of a noisy environment. It uses sequences of inversion pulses to suppress the environmental perturbations by periodically refocusing them ...
Souza, Alexandre M., Suter, Dieter, Álvarez, Gonzalo A.   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Block-building performance test using a virtual reality head-mounted display in children with intermittent exotropia. [PDF]

Eye (Lond), 2021
Chung SA, Choi J, Jeong S, Ko J.
europepmc   +1 more source