Results 131 to 140 of about 11,576,501 (264)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Building performance optimization of net zero-energy buildings

open access: yes, 2015
Building performance optimization (BPO) paired with building performance simulation (BPS) is a promising solution for evaluating many different design options and obtaining the optimal or near-optimal solution for a given objective or combination of ...
Pagliano, L.   +7 more
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

An implementation of co-simulation for performance prediction of innovative integrated HVAC systems in buildings [PDF]

open access: yes, 2009
Integrated performance simulation of buildings and heating, ventilation and air-conditioning (HVAC) systems can help reducing energy consumption and increasing level of occupant comfort. However, no singe building performance simulation (BPS) tool offers
Hensen, Jan L. M.   +8 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Towards more effective use of building performance simulation in design

open access: yes, 2004
This paper discusses some issues which hinder effective use of building performance simulation in building design, and some approaches towards better and more efficient use of this important but underutilized technology.
Timmermans, H.J.P.   +2 more
core  

Optimizing the total energy consumption and CO2 emissions by distributing computational workload among worldwide dispersed data centers [PDF]

open access: yes, 2015
Major internet service providers have built and are currently building the world's largest data centres (DCs), which has already resulted in significant global energy consumption.
Van Schie, Frank T.   +6 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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