Results 121 to 130 of about 11,576,501 (264)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Building performance simulation for sustainable buildings [PDF]
, 2010 This paper aims to provide a general view of the background and current state of building performance simulation, which has the potential to deliver, directly or indirectly, substantial benefits to building stakeholders and to the environment.
Hensen, J.L.M., Hensen, JLM Jan
core +3 more sources
Gaussian-Process-Based Emulators for Building Performance Simulation [PDF]
In this paper we present a novel emulator of a building simulator for the simulation-assisted design of high performance buildings. Our emulator is based on Gaussian-Process (GP) regression models.
Khan, Mohammad Emtiyaz +2 more
core +2 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Architect Friendly: a Comparison of Ten Different Building Performance Simulation Tools [PDF]
, 2009 Performance Simulation tools BPS is available internationally. The users of those tools are mainly researchers, physicists and experts who value empirical validation, analytical verification and calibration of uncertainty as defined by e.g.
J. Hensen +17 more
core +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
A simulation approach to the evaluation of coupled heat and mass transfer in buildings
, 1991 This paper describes the techniques used within the ESP environment to simulate coupled heat and mass flows in integrated building and plant systems.
Hensen, J.L.M. +3 more
core
, 2012 A numerical analysis with Computational Fluid Dynamics (CFD) is performed to investigate the influence of building width on the performance of a venturi-shaped roof (called Ventec roof) for natural ventilation. The specific roof configuration is intended
Blocken, B.J.E. +9 more
core +1 more source
A machine learning algorithm to improve building performance modeling during design. [PDF]
MethodsX, 2020 Chokwitthaya C +3 more
europepmc +1 more source