Results 131 to 140 of about 3,800,881 (287)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Building high-performance knowledgement institutions for water management [PDF]
Institutional development / Research institutes / Performance ...
International Water Management Institute, IWMI-TATA Water Policy Program
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Sustainable Building Performance and Design: a guide to finding information [PDF]
, 2015 Using the library to find books and journal articles on energy efiicient and sustainable ...
Geoff Morgan
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Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Nonprofit "Capacity-Building Orientation": The Role of Learning in Building Nonprofit Performance [PDF]
, 2005 Amidst increasing attention to nonprofit performance, interest in nonprofit capacity building activities has understandably intensified. A natural outgrowth of this interest is an expansion in the number and range of nonprofit capacity-building providers
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
A machine learning algorithm to improve building performance modeling during design. [PDF]
MethodsX, 2020 Chokwitthaya C +3 more
europepmc +1 more source
Building envelope design as a contribution for improvement of urban spaces and social housing environmental quality [PDF]
, 2008 The design of building envelope and the definition of its elements, can influence both the quality of the external spaces perception and the living standard referred to internal building spaces. This improvement depends by the planning of some component
ARBIZZANI, Eugenio +3 more
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