Results 61 to 70 of about 13,297,292 (248)

Introducing uncertainty and sensitivity analysis in non-modifiable building performance software [PDF]

open access: yes, 2006
If using simulation tools for predicting the overall building performance, important decisions concerning the input of those tools need to be taken. The input is based on experience but also assumptions.
Hopfe, C.J.   +5 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Minimum number of simulation runs for reliable building energy and peak load prediction at different building scales: a study on stochastic shade adjustment

open access: yesJournal of Asian Architecture and Building Engineering, 2020
This paper investigates the impact of uncertain shade behavior on three facades (east, south and west) on energy performance. A previously developed stochastic shade behavior model and an occupancy model were used to conduct building co-simulation for ...
Jian Yao
doaj   +1 more source

On system simulation for building performance evaluation

open access: yes, 1995
This paper gives an overview and examples of various approaches to system simulation in buildings. Advantages and disadvantages of the different methods with respect to problems commonly encountered in building performance evaluation are described ...
Hensen, J.L.M., Hensen, JLM Jan
core  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Scan-to-EDTs: Automated Generation of Energy Digital Twins from 3D Point Clouds

open access: yesBuildings
Digital Twins (DTs) are transforming construction and energy management sectors by integrating 3D surveying, monitoring, Building Performance Simulation (BPS), and Building Energy Simulation (BES) from the earliest design or retrofit stages.
Oscar Roman   +5 more
doaj   +1 more source

Implementation and demonstration of a building simulation based testbed for assessment of data centre multi-domain control strategies

open access: yes, 2017
Publisher Copyright: © 2017 Building Simulation Conference Proceedings. All rights reserved.The traditional data centre (DC) infrastructure is being significantly extended by modern information technology (IT) trends on one side, and lasting calling for ...
Zavřel, Vojtěch   +2 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

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