Results 51 to 60 of about 13,297,292 (248)

A fast response performance simulation screening tool in support of early stage building design [PDF]

open access: yes, 2020
This paper aims to introduce the development of a simplified dynamic building energy simulation screening tool aimed to support early stage building design and feasibility studies while considering the lack of resources typical of those stages of the ...
Marco Picco   +3 more
core   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Effects of different architectural solutions on the thermal behaviour in an unconditioned rural building. The case of an Italian winery

open access: yesJournal of Agricultural Engineering, 2018
Referring to the wine sector, in the Mediterranean area, most of the wine farms make use of unconditioned above-ground buildings constructed without a specific attention to temperature control, where indoor temperatures easily show trends in disagreement
Daniele Torreggiani   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Analysis and Simulation on Energy Performance Based Design

open access: yesMegaron, 2011
The definition of sustainability varies depending on the sector to which it is related. In the building sector, sustainability mainly covers “high performance building” requirements.
Gülsu ULUKAVAK HARPUTLUGİL
doaj  

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Sustainable building: Achieving thermal comfort in hot and humid climate using building performance simulation

open access: yesSustinere: Journal of Environment and Sustainability
The scientific community has established a clear link between the built environment and various environmental problems. Various strategies have been implemented to mitigate the negative impacts of buildings and to address broader environmental ...
Niniek Pratiwi   +4 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

People in building performance simulation

open access: yes, 2019
(no german description): SCOPE: This chapter addresses the representation of people's presence and behavior in building performance simulation.
Tahmasebi, Farhang, Mahdavi, Ardeshir
core   +4 more sources

Building Performance Analysis and Simulation: We’ve Come a Long Way

open access: yesBuildings, 2014
Back in 1981, when I started doing building energy performance simulation for pre-design and energy efficiency retrofit work, building simulation was in its infancy. [...]
V. Ismet Ugursal
doaj   +1 more source

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