Results 31 to 40 of about 169,526 (268)

Dynamic Simulation of Heat Transfer through External Building Constructions

Журнал інженерних наук, 2019
In the paper, some approaches to dynamic modeling of heat transfer through external building constructions are presented. The model of heat transfer dynamics through a wall was designed on the base of mathematical describing of an energy balance for the ...
Pitel J., Khovanskyi S., Pavlenko I., Mizakova J.   +3 more
doaj   +1 more source

Methodology to characterize a residential building stock using a bottom-up approach: a case study applied to Belgium

International Journal of Sustainable Energy Planning and Management, 2014
In the last ten years, the development and implementation of measures to mitigate climate change have become of major importance. In Europe, the residential sector accounts for 27% of the final energy consumption [1], and therefore contributes ...
Samuel Gendebien, Emeline Georges, Stéphane Bertagnolio, Vincent Lemort   +3 more
doaj   +1 more source

Mitigating the Energy Consumption and Carbon Emissions of a Residential Area in a Tropical City Using Digital Twin Technology: A Case Study of Bertam, Penang

Buildings
As of 2022, roughly 79.8% of Malaysia’s population resides in urban areas, increasing the population density of its cities. The hot and humid climate in Malaysia necessitates the constant use of air conditioning, especially in cities, resulting in high ...
Nur Haziqah Mohamad Zaidi, Chin Haw Lim, Halim Razali   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Combined Effects of Exterior Shading and A/C Heat Rejection on Building Energy Consumption and Indoor Air Pollution Exposure

Buildings, 2023
Exterior shading devices and outdoor units can be closely coupled since these two building components are commonly installed next to each other. This study uses a coupled EnergyPlus-Fluent modeling approach to examine how a combination of exterior ...
Xuyang Zhong, Zhiang Zhang, Ruijun Zhang, Zijian Wu   +3 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An Advanced Fractional Order Method for Temperature Control

Fractal and Fractional, 2023
Temperature control in buildings has been a highly studied area of research and interest since it affects the comfort of occupants. Commonly, temperature systems like centralized air conditioning or heating systems work with a fixed set point locally set
Ricardo Cajo, Shiquan Zhao, Isabela Birs, Víctor Espinoza, Edson Fernández, Douglas Plaza, Gabriela Salcan-Reyes   +6 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source