Results 41 to 50 of about 1,174,972 (306)

Combined Effects of Exterior Shading and A/C Heat Rejection on Building Energy Consumption and Indoor Air Pollution Exposure

open access: yesBuildings, 2023
Exterior shading devices and outdoor units can be closely coupled since these two building components are commonly installed next to each other. This study uses a coupled EnergyPlus-Fluent modeling approach to examine how a combination of exterior ...
Xuyang Zhong   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Lipopolysaccharide Membrane Building and Simulation [PDF]

open access: yes, 2015
While membrane simulations are widely employed to study the structure and dynamics of various lipid bilayers and membrane proteins in the bilayers, simulations of lipopolysaccharides (LPS) in membrane environments have been limited due to their structural complexity, difficulties in building LPS-membrane systems, and lack of the appropriate molecular ...
Sunhwan, Jo   +6 more
openaire   +2 more sources

Integrated building performance simulation [PDF]

open access: yes, 2001
This paper justifies the need for an integrated approach to building performance assessment and provides examples of the technical appraisals that may then be enabled.
Clarke, J.A.
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

An Advanced Fractional Order Method for Temperature Control

open access: yesFractal and Fractional, 2023
Temperature control in buildings has been a highly studied area of research and interest since it affects the comfort of occupants. Commonly, temperature systems like centralized air conditioning or heating systems work with a fixed set point locally set
Ricardo Cajo   +6 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Experimental and Numerical Analysis of Temperature Reduction Potentials in the Heating Supply of an Unrenovated University Building

open access: yesEnergies, 2023
Lowering the temperatures in heating systems is the key to decarbonizing the heat supply in the building sector, because it is a door opener to greater integration of renewable heat, the use of excess heat and to improve compatibility for heat pumps ...
David Sauerwein   +2 more
doaj   +1 more source

Simulation of Industrialised Building System components production [PDF]

open access: yes, 2006
The construction of IBS building should starts with the production of the IBS components and the production process is the main activity concerned in the IBS production plant.
Makhtar, Ahmad Mahir   +3 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

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