Results 51 to 60 of about 8,841,531 (329)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Simulation of Industrialised Building System components production [PDF]
, 2006 The construction of IBS building should starts with the production of the IBS components and the production process is the main activity concerned in the IBS production plant.
Makhtar, Ahmad Mahir +3 more
core
Lipopolysaccharide Membrane Building and Simulation [PDF]
, 2015 While membrane simulations are widely employed to study the structure and dynamics of various lipid bilayers and membrane proteins in the bilayers, simulations of lipopolysaccharides (LPS) in membrane environments have been limited due to their structural complexity, difficulties in building LPS-membrane systems, and lack of the appropriate molecular ...
Sunhwan, Jo +6 more
openaire +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
An Advanced Fractional Order Method for Temperature Control
Fractal and Fractional, 2023 Temperature control in buildings has been a highly studied area of research and interest since it affects the comfort of occupants. Commonly, temperature systems like centralized air conditioning or heating systems work with a fixed set point locally set
Ricardo Cajo +6 more
doaj +1 more source
On the efficiency of quantization-based integration methods for building simulation
, 2018 Models describing energy consumption, heating, and cooling of buildings usually impose difficulties to the numerical integration algorithms used to simulate them.
Federico Bergero +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Energies, 2023 Lowering the temperatures in heating systems is the key to decarbonizing the heat supply in the building sector, because it is a door opener to greater integration of renewable heat, the use of excess heat and to improve compatibility for heat pumps ...
David Sauerwein +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Delivering building simulation information via new communication media [PDF]
, 2007 Often, the goal of understanding how the building works and the impact of design decisions is hampered by limitations in the presentation of performance data.
Clarke, Joseph Andrew +3 more
core +2 more sources