Results 61 to 70 of about 8,841,531 (329)

Improving energy modeling of large building stock through the development of archetype buildings [PDF]

open access: yes, 2011
12th Conference of International Building Performance Simulation ...
Ballarini, Ilaria   +3 more
core  

From White to Black-Box Models: A Review of Simulation Tools for Building Energy Management and Their Application in Consulting Practices

open access: yesEnergies
Buildings consume significant energy worldwide and account for a substantial proportion of greenhouse gas emissions. Therefore, building energy management has become critical with the increasing demand for sustainable buildings and energy-efficient ...
Amir Shahcheraghian   +2 more
semanticscholar   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Simulation and BIM in building design, commissioning and operation: a comparison with the microelectronics industry [PDF]

open access: yes, 2009
Analogy between the Microelectronics and Building industries is explored with the focus on design, commissioning and operation processes. Some issues found in the realisation of low energy buildings are highlighted and techniques gleaned from ...
Tuohy, Paul Gerard
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

A co-operating solver approach to building simulation [PDF]

open access: yes, 2004
This paper describes the co-operating solver approach to building simulation as encapsulated within the ESP-r system.
Clarke, J. A., Tang, D.
core  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

ANALYSIS OF ENERGY-EFFICIENT HOUSE LAYOUT DESIGN IN TROPICAL CLIMATE

open access: yesDimensi: Journal of Architecture and Built Environment, 2021
Energy-efficient residential provision is an essential concern for the present and future city development. Currently, the residential buildings contribute approximately 37.5% to significant energy consumption and carbon emissions, which mainly used for ...
Aisyah Zakiah
doaj   +1 more source

The development of a generic systems-level model for combustion-based domestic cogeneration [PDF]

open access: yes, 2008
The provision of heat and power to dwellings from micro-cogeneration systems is gaining credence around the developed world as a possible means to reduce the significant carbon emissions associated with the domestic sector. However, achieving the optimum
Ferguson, Alex   +3 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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