Results 61 to 70 of about 811,371 (313)
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Green building future: algal application technology
In the context of rising global energy demands driven by population growth and urbanization, the construction industry significantly contributes to greenhouse gas emissions during the construction phase and subsequent energy consumption.
Özgür Eren Zariç +2 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Sign advertising the construction of the new Business and General Studies building, 1974
Sign advertising the construction of Swinburne College of Technology's new building for Business and General Studies Department in June 1974. Sign reads: Swinburne College of Technology new building for Business and General Studies Departments ...
Swinburne College of Technology
core
Building m-health technology to promote breastfeeding
Objective: to develop an m-health technology to promote breastfeeding in nursing mothers. Methods: methodological study, carried out from February 2020 to July 2021. Technological development application, following Pressman's prototyping model.
Jéssika Roberta Firme de Moura Santos +6 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Administration Building from the West, 1980s
Administration Building, from the West, showing part of the old Domestic Science Building, the Library, the Business Arts Building (BA), and the Swinburne Technical ...
Swinburne College of Technology
core
Building ceramics – raw materials, technology, and economic importance
The ceramics industry plays a key role in the economy, supplying materials essential for construction, electronics, metallurgy, and many other industries.
Anna Konstanciak
doaj +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source

