Results 131 to 140 of about 4,751,330 (349)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Datasets of Faults in Variable Air Volume Terminal Units in a Multi-Zone Commercial Building
Scientific DataFaults in HVAC systems can decrease system efficiency and equipment lifespan, leading to 5%–30% of energy consumption being wasted in commercial buildings.
Sungkyun Jung, Yeobeom Yoon, Piljae Im
doaj +1 more source
BuildingsPrecast concrete structures are popular in the building industry because of their high efficiency and environmental friendliness. In this paper, the U-type reinforcement ferrule connection technique was applied to study the seismic performance of precast
Peiqi Chen +4 more
doaj +1 more source
Affine Buildings and Tropical Convexity
, 2007 The notion of convexity in tropical geometry is closely related to notions of convexity in the theory of affine buildings. We explore this relationship from a combinatorial and computational perspective.
Joswig, Michael +2 more
core
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Study on the Bond Performance of Epoxy Resin Concrete with Steel Reinforcement
BuildingsEpoxy resin concrete, characterized by its superior mechanical properties, is frequently utilized for structural reinforcement and strengthening. However, its application in structural members remains limited.
Peiqi Chen +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
How to build a nestbox in a wall cavity [PDF]
, 2015 Building conservation is fraught with ethical dilemmas. At one extreme there is pressure to freeze buildings at a particular point in time and another to modernise them beyond all recognition.
Hippisley-Cox, Charles
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
"Build, build, build" - new permitted development rights [PDF]
, 2020 Reviews reforms to the Town and Country Planning (General Permitted Development) (England) Order 2015 Pt 20, to permit construction of up to two extra storeys on many purpose-built blocks of flats, without planning permission. Examines the restrictions on the permitted development right, the factors relevant to prior approval applications, the role of ...
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