Results 31 to 40 of about 775,507 (192)

Correlation Between Maximal Tongue Pressure and Swallowing Function in Spinal and Bulbar Muscular Atrophy

Frontiers in Neurology, 2021
Background: Spinal and bulbar muscular atrophy (SBMA) is an X-lined motor neuron disease characterized by progressive muscle weakness, bulbar palsy, and dysphagia.
Dae-Won Gwak, Seung-Hwan Jung, Yu-Sun Min, Jin-Sung Park, Hee-Jin Cho, Donghwi Park, Min Woo Hong, Min-Gu Kang   +7 more
doaj   +1 more source

Clinical and imaging features of "heart appearance" isolated cerebral infarction in bilateral medial pons-medulla oblongata

陆军军医大学学报, 2023
Objective To investigate the clinical and imaging features of the characteristic "heart appearance" isolated cerebral infarction involving bilateral pons-medulla oblongata.
DIAO Shengpeng, WU Weifeng, LIU Aiqun, PENG Zhongxing, HONG Mingfan   +4 more
doaj   +1 more source

Progress and challenges in directing the differentiation of human iPSCs into spinal motor neurons

Frontiers in Cell and Developmental Biology, 2023
Motor neuron (MN) diseases, including amyotrophic lateral sclerosis, progressive bulbar palsy, primary lateral sclerosis and spinal muscular atrophy, cause progressive paralysis and, in many cases, death.
Cristina Marisol Castillo Bautista, Jared Sterneckert, Jared Sterneckert   +2 more
doaj   +1 more source

Pyramidal system involvement in progressive supranuclear palsy – a clinicopathological correlation

BMC Neurology, 2019
Background We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).
Zuzana Stejskalova, Zdenek Rohan, Robert Rusina, Adam Tesar, Jaromir Kukal, Gabor G. Kovacs, Ales Bartos, Radoslav Matej   +7 more
doaj   +1 more source

A longitudinal study of motor, oculomotor and cognitive function in progressive supranuclear palsy

, 2013
ObjectiveWe studied the annual change in measures of motor, oculomotor and cognitive function in progressive supranuclear palsy. This had twin objectives, to assess the potential for clinical parameters to monitor disease progression in clinical trials ...
Boyd C P Ghosh, Roger H. S. Carpenter, Roger H S Carpenter, James B. Rowe, Carpenter, Roger H.S., Rowe, James B., James B Rowe, Ghosh, Boyd C.P., Boyd C. P. Ghosh, Ghosh Boyd C. P., Rowe James B., Carpenter Roger H. S.   +11 more
core   +1 more source

Disrupted resting-state functional connectivity in progressive supranuclear palsy [PDF]

, 2015
BACKGROUND AND PURPOSE: Studies on functional connectivity in progressive supranuclear palsy have been restricted to the thalamus and midbrain tegmentum.
Sbardella E, Formica A, Tona F, Petsas N, Filippini N, BOLOGNA, Matteo, Piattella MC, BERARDELLI, Alfredo, PANTANO, Patrizia   +8 more
core   +1 more source

A Korean family with AGel amyloidosis presenting with progressive facial and bulbar palsies

Annals of Clinical Neurophysiology, 2022
AGel amyloidosis is an autosomal dominantly inherited disease caused by a GSN mutation, and affected patients typically present with the clinical triad of corneal lattice dystrophy, progressive cranial neuropathy, and cutis laxa. We report a Korean family with AGel amyloidosis with predominant manifestations of facial and bulbar muscle weakness.
Minsung Kang, Jin-Hong Shin, Dae-Seong Kim   +2 more
openaire   +1 more source

Low dose Amantadine and Escitalopram combination in Atypical Parkinsonian disorders- A Retrospective chart review

European Psychiatry, 2023
Introduction The response to conventional antiparkinsonian medications is elusive in atypical parkinsonian disorders. Improvement in parkinsonian symptoms in atypical parkinsonian disorders has been reported with anecdotal use of Amantadine. The role of
S. M. Tripathi, P. Chutia
doaj   +1 more source

Clinical Conditions “Suggestive of Progressive Supranuclear Palsy”—Diagnostic Performance [PDF]

, 2020
Background: The Movement Disorder Society diagnostic criteria for progressive supranuclear palsy introduced the diagnostic certainty level “suggestive of progressive supranuclear palsy” for clinical conditions with subtle signs, suggestive of the disease.
Grimm, M.-J., Rowe, J.B., Grossman, M., Nilsson, C., Gelpi, E., Höglinger, G.U., Arzberger, T., Ferguson, L., van Swieten, J.C., Respondek, G., Irwin, D.J., Troakes, C., for the Movement Disorder Society-Endorsed PSP Study Group, Pantelyat, A., Roeber, S., Stamelou, M., Compta, Y., Giese, A., Piot, I., Rajput, A., Meissner, W.G.   +20 more
core   +4 more sources

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean, Lena C. O’Flynn, Michelle Ciucci, Cynthia Fox, Jessica E. Huber, Supraja Anand, Maira Rozenfeld Olchik, Jibrin S. Usman, Adam P. Vogel, Bettina Aguiar, Diana Khasanova, Dharshini Manoharan, Lorraine Ramig, Angela Roberts, Federico Rodriguez‐Porcel, Kristina Simonyan, Julie M. Barkmeier‐Kraemer   +16 more
wiley   +1 more source