Results 31 to 40 of about 4,299 (194)

Disease severity and progression in progressive supranuclear palsy and multiple system atrophy: validation of the NNIPPS--Parkinson Plus Scale. [PDF]

PLoS ONE, 2011
The Natural History and Neuroprotection in Parkinson Plus Syndromes (NNIPPS) study was a large phase III randomized placebo-controlled trial of riluzole in Progressive Supranuclear Palsy (PSP, n = 362) and Multiple System Atrophy (MSA, n = 398).
Christine A M Payan, François Viallet, Bernhard G Landwehrmeyer, Anne-Marie Bonnet, Michel Borg, Franck Durif, Lucette Lacomblez, Frédéric Bloch, Marc Verny, Jacques Fermanian, Yves Agid, Albert C Ludolph, Peter N Leigh, Gilbert Bensimon, NNIPPS Study Group   +14 more
doaj   +3 more sources

Uncovering distinct progression patterns of tau deposition in progressive supranuclear palsy using [18F]Florzolotau PET imaging and subtype/stage inference algorithmResearch in context [PDF]

EBioMedicine, 2023
Summary: Background: Progressive supranuclear palsy (PSP) is a primary 4-repeat tauopathy with diverse clinical phenotypes. Previous post-mortem studies examined tau deposition sequences in PSP, but in vivo scrutiny is lacking.
Jimin Hong, Jiaying Lu, Fengtao Liu, Min Wang, Xinyi Li, Christoph Clement, Leonor Lopes, Matthias Brendel, Axel Rominger, Tzu-Chen Yen, Yihui Guan, Mei Tian, Jian Wang, Chuantao Zuo, Kuangyu Shi, Jian Wang, Fengtao Liu, Chuantao Zuo, Jianjun Wu, Yimin Sun, Ping Wu, Yilin Tang, Jue Zhao, Bin Wu, Bo Shen, Jiaying Lu, Xinyue Zhou, Xinyi Li, Huiwei Zhang, Jingjie Ge, Minjia Chen, Zizhao Ju   +31 more
doaj   +2 more sources

Unexpected gender differences in progressive supranuclear palsy reveal efficacy for davunetide in women

Translational Psychiatry, 2023
Progressive supranuclear palsy (PSP) is a pure tauopathy, implicating davunetide, enhancing Tau-microtubule interaction, as an ideal drug candidate. However, pooling patient data irrespective of sex concluded no efficacy.
Illana Gozes, Guy Shapira, Alexandra Lobyntseva, Noam Shomron   +3 more
doaj   +2 more sources

Lymphoma Presenting as Acute-Onset Dysphagia [PDF]

Case Reports in Neurological Medicine, 2015
A 61-year-old man with recent Bell’s palsy developed acute vocal cord paralysis causing severe dysphagia. CSF analysis showed elevated protein and a normal cell count; contrast-enhanced MRI of the brain was normal. He was treated with IVIG for a presumed
Daniel B. Simmons, Andrew W. Bursaw
doaj   +2 more sources

Injury of the arcuate fasciculus in a patient with progressive bulbar palsy

Neural Regeneration Research, 2016
Min Cheol Chang, Han Do Lee, Sung Ho Jang   +2 more
doaj   +3 more sources

Progressive Bulbar Palsy Care: Exploring the Potential of Functional MRI for Early Detection

Yemeni Journal for Medical Sciences
Progressive bulbar palsy (PBP) is a neurodegenerative disorder impacting motor neurons involved in speech, swallowing, and breathing. Early diagnosis is challenging due to limited diagnostic tools. Functional MRI (fMRI) holds promise for detecting early biomarkers and tracking disease progression, potentially improving clinical management.
Komalasari, Rita
openaire   +3 more sources

The first description of idiopathic progressive bulbar palsy. [PDF]

Journal of Neurology, Neurosurgery and Psychiatry, 1993
J D Mitchell, R J Swingler
exaly   +3 more sources

Progressive bulbar palsy with facial diplegia and proximal weakness diagnosed as juvenile-onset myasthenia gravis

Annals of Indian Academy of Neurology, 2023
Rajesh Verma, Rajarshi Chakraborty, Pooja Tripathi   +2 more
doaj   +3 more sources

Basilar invagination: A mimicker of bulbar-onset amyotrophic lateral sclerosis

eNeurologicalSci, 2021
Amyotrophic lateral sclerosis (ALS) is characterized by progressive onset motor deficits with heterogenous presentations ranging from dysarthria to foot drop.
Jason Seng Hong Tan, Shirley Lee, Fu Liong Hiew   +2 more
doaj   +1 more source

Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2. [PDF]

, 2013
Childhood onset motor neuron diseases or neuronopathies are a clinically heterogeneous group of disorders. A particularly severe subgroup first described in 1894, and subsequently called Brown-Vialetto-Van Laere syndrome, is characterized by progressive ...
Land, John M., Lin, JP, Antony, J, Brandner, Sebastian, Broomfield, Alexander, Menezes, MP, Oppenheim, Marcus, Horvath, Rita, Pandraud, Amelie, Lin, Jean-Pierre, Scherer, Steven S., Abrams, Alexander J., Shah, Ayaz H, Sugano, K, Lim, MJ, Scoto, Mariacristina, Carpenter, Kevin, Megarbane, Andre, Gold, Wendy, Land, JM, Ng, Joanne, Phadke, Rahul, Matsubara, K, Mathew, Ann A., Lim, Ming J., Shah, AH, Lek, Monkol, Foley, AR, Matsubara, Kazuo, Hargreaves, Iain, Foley, A. Reghan, Züchner, S, Manzur, Adnan Y., Lim, Ming J, McCullagh, BG, Mathew, Ann A, Reilly, Mary M, McGarvey, Michael L, Olpin, S, Urtizberea, JA, Scoto, M, Webster, R, Lek, M, Olpin, Simon, Wang, Min X, Reilly, MM, Farrell, Michael O., Burns, J, Houlden, H, McCullagh, B. Gary, Forman, Eva, Burns, Joshua, Straub, Volker, Hargreaves, IP, Houlden, Henry, Gonzalez, Michael A., Megarbane, A, Jungbluth, Heinz, O'Byrne, JJ, Scherer, Steven S, Pandraud, A, Menezes, Manoj P., Hughes, Imelda, O’Byrne, James J, Gonzalez, Michael A, Gold, W, McCullagh, B Gary, Muntoni, Francesco, Züchner, Stephan, Scherer, SS, Baxter, PS, Shah, Ayaz H., Jungbluth, Heinz; id_orcid, Christodoulou, John, O'Byrne, James J, McGarvey, ML, O'Brien, Katherine, Clayton, P, Broomfield, A, Menezes, Manoj P, King, MD, Yonezawa, Atsushi, O'Byrne, James J., Baxter, Peter S, McGarvey, Michael L., Prasad, M, Ng, J, Straub, V, Land, John M, Muntoni, F, Abrams, AJ, Lin, J-P, O’Brien, Katherine, Al-Odaib, A, Rahman, S, Al-Odaib, Ahmad, Zuechner, Stephan, Clayton, Peter, Manzur, Adnan Y, Phadke, R, Reilly, Mary M., Jungbluth, H, Farrell, Michael O, Prasad, Manish, Ouvrier, Robert A, Farrell, MO, Antony, Jayne, Horvath, R, Foley, A Reghan, Forman, E, Manzur, AY, Brandner, S, Hargreaves, I, Gonzalez, MA, Christodoulou, J, Rahman, Shamima, King, Mary D, King, Mary D., Sugano, Kumiko, Hughes, I, Ouvrier, RA, Wang, Min X., Ouvrier, Robert A., Urtizberea, J. Andoni, Webster, Richard, Abrams, Alexander J, Urtizberea, J Andoni, Baxter, Peter S., O'Brien, K, Wang, MX, Mathew, AA, Oppenheim, M, Carpenter, K, Yonezawa, A, Zuechner, S   +134 more
core   +1 more source