Results 41 to 50 of about 4,299 (194)

Correlation Between Maximal Tongue Pressure and Swallowing Function in Spinal and Bulbar Muscular Atrophy

Frontiers in Neurology, 2021
Background: Spinal and bulbar muscular atrophy (SBMA) is an X-lined motor neuron disease characterized by progressive muscle weakness, bulbar palsy, and dysphagia.
Dae-Won Gwak, Seung-Hwan Jung, Yu-Sun Min, Jin-Sung Park, Hee-Jin Cho, Donghwi Park, Min Woo Hong, Min-Gu Kang   +7 more
doaj   +1 more source

Disease duration of progression is helpful in identifying isolated bulbar palsy of amyotrophic lateral sclerosis [PDF]

BMC Neurology, 2021
Abstract Background Compared with typical bulbar onset amyotrophic lateral sclerosis (ALS), isolated bulbar palsy (IBP), an often under-understood variant of ALS, is characterized by symptoms confined to bulbar region for extended periods and relative preservation of limb and ventilation function.
Huagang Zhang, Lu Chen, Jinzhou Tian, Dongsheng Fan   +3 more
openaire   +3 more sources

Clinical and imaging features of "heart appearance" isolated cerebral infarction in bilateral medial pons-medulla oblongata

陆军军医大学学报, 2023
Objective To investigate the clinical and imaging features of the characteristic "heart appearance" isolated cerebral infarction involving bilateral pons-medulla oblongata.
DIAO Shengpeng, WU Weifeng, LIU Aiqun, PENG Zhongxing, HONG Mingfan   +4 more
doaj   +1 more source

Progress and challenges in directing the differentiation of human iPSCs into spinal motor neurons

Frontiers in Cell and Developmental Biology, 2023
Motor neuron (MN) diseases, including amyotrophic lateral sclerosis, progressive bulbar palsy, primary lateral sclerosis and spinal muscular atrophy, cause progressive paralysis and, in many cases, death.
Cristina Marisol Castillo Bautista, Jared Sterneckert, Jared Sterneckert   +2 more
doaj   +1 more source

Low dose Amantadine and Escitalopram combination in Atypical Parkinsonian disorders- A Retrospective chart review

European Psychiatry, 2023
Introduction The response to conventional antiparkinsonian medications is elusive in atypical parkinsonian disorders. Improvement in parkinsonian symptoms in atypical parkinsonian disorders has been reported with anecdotal use of Amantadine. The role of
S. M. Tripathi, P. Chutia
doaj   +1 more source

Structural Lung Disease in Children and Adolescents With Severe Neurological Disorders. [PDF]

Pediatr Pulmonol
ABSTRACT Background and Objective Children with severe neurological disorders are at risk of secondary respiratory morbidity due to impaired airway clearance and dysphagia, but systematic data on structural lung changes remain scarce. Methods We retrospectively analyzed all clinically indicated chest CT examinations at a tertiary care center (2015–2025)
Bernard DAF, Dahl C, Salhöfer L, Pauly A, Steindor M, Olivier M, Schara-Schmidt U, Welsner M, Schweiger B, Zensen S, Drews MA, Haubold J, Forsting M, Umutlu L, Opitz M, Stehling F.   +15 more
europepmc   +2 more sources

Pyramidal system involvement in progressive supranuclear palsy – a clinicopathological correlation

BMC Neurology, 2019
Background We aimed to produce a detailed neuropathological analysis of pyramidal motor system pathology and provide its clinical pathological correlation in cases with definite progressive supranuclear palsy (PSP).
Zuzana Stejskalova, Zdenek Rohan, Robert Rusina, Adam Tesar, Jaromir Kukal, Gabor G. Kovacs, Ales Bartos, Radoslav Matej   +7 more
doaj   +1 more source

Case report and literature review: Novel compound heterozygous FIG4 variants causing both of peripheral and central nervous system defects

Frontiers in Pediatrics, 2022
BackgroundPathogenic variants in the FIG4 gene have been described to be associated with a diverse spectrum of syndromes, such as autosomal recessive bilateral temporooccipital polymicrogyria (OMIM 612691), autosomal dominant amyotrophic lateral ...
Yonglin Yu, Hongwei Yin, Changli Ma, Xiaoyi Jia, Wencong Chen, Haifeng Li, Ke Wu, Ke Wu   +7 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Case Report: Guillain-Barré Syndrome Characterized by Severe Headache Associated With Metabotropic Glutamate Receptor 5 Antibody

Frontiers in Immunology, 2022
Autoantibodies to metabotropic glutamate receptor 5 (mGluR5) are known to be the cause of autoimmune encephalitis, particularly limbic encephalitis, closely related to Hodgkin’s lymphoma (HL).
Weiqian Yan, Cheng Zhao, Hainan Zhang, Zhiping Hu, Chunyu Wang   +4 more
doaj   +1 more source