This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
The structure of a complex, asymmetric coronal mass ejection revealed by 17 spacecraft across the inner heliosphere. [PDF]
Luspay-Kuti A +30 more
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Layered grouting reinforcement technology for coal-rock composite roof: A treatment system based on model experiments. [PDF]
Liao Z, Li P, Zhao X, Wu G, Zhao L.
europepmc +1 more source
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara +3 more
wiley +1 more source
Nanoscale Confinement Enhances Ultrafast Demagnetization. [PDF]
Windsor YW +23 more
europepmc +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Sensor-Informed Motion-Continuity Control of Shared-Return Electro-Hydraulic Actuator Networks Under Neighboring-Branch Disturbances. [PDF]
Wu T, Zhao L, Lin G, Gong S.
europepmc +1 more source
Integrated porosity estimation of partially saturated sand-hematite mixtures using electrical resistivity and elastic wave velocity. [PDF]
Lee JS, Kang HS, Lee D, Kim SY.
europepmc +1 more source
Rhizosphere bacterial and fungal community structure varies among field-grown <i>Mentha spicata</i> accession plots with different essential oil profiles. [PDF]
Juhász Á +5 more
europepmc +1 more source

