Results 51 to 60 of about 5,242,910 (302)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Design dimensions of experience rooms for service test drives : case studies in several service contexts [PDF]

open access: yes, 2010
Purpose - The objective of this exploratory study is to analyse "test drives" of service offerings in a variety of service contexts by applying existing design dimensions of experience rooms in order to develop some principles to assist service designers
Edvardsson, Bo   +8 more
core   +1 more source

Rectangular silos; Interaction of structure and stored bulk solid [PDF]

open access: yes, 2002
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The main aim of this research is directed towards the study of thin-walled rectangular planform silos with a view to maximising their structural efficiency.
Goodey, Richard J
core   +6 more sources

Cost Optimization in Sintering Process on the Basis of Bulk Queueing System with Diverse Services Modes and Vacation

open access: yesMathematics
This research investigated a single bulk server queuing model where service modes and server vacations are dependent on the number of clients. The server operates in three different service modes: single service, fixed batch service, and variable batch ...
Subramani Palani Niranjan   +2 more
doaj   +1 more source

A Novel Analytic Technique for the Service Station Reliability in a Discrete-Time Repairable Queue

open access: yesJournal of Applied Mathematics, 2013
This paper presents a decomposition technique for the service station reliability in a discrete-time repairable GeomX/G/1 queueing system, in which the server takes exhaustive service and multiple adaptive delayed vacation discipline.
Renbin Liu, Yinghui Tang
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Elastic properties of Zr-based bulk metallic glasses studied by resonant ultrasound spectroscopy [PDF]

open access: yes
We report measurements of the elastic properties of Zr-based bulk metallic glasses, Zr52.5Cu17.9Ni14.6Al10Ti5, Zr50Cu30Ni10Al10, and Zr50Cu40Al10 between 5 K and 300 K.
Zhang, Zhiying   +4 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Predictable uncertainty about terminal operations in the sea

open access: yesTransport, 2010
This paper considers a problem of planning short term operations in a bulk terminal faced by port management when making tactical decisions. Ship loading and discharging, cargo stocking, the maintenance and service of facility equipment are regular ...
Svjetlana Hess, Mirano Hess
doaj   +3 more sources

A Bulk-Service Queueing Problem with Variable Capacity

open access: yesJournal of the Royal Statistical Society Series B: Statistical Methodology, 1961
SUMMARY The bulk-service queueing problem solved by Bailey (1954) has been extended to the case in which the maximum number of units to be taken for service is not constant, but depends upon the number of units already present with the server as well as upon the capacity.
openaire   +2 more sources

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