Results 111 to 120 of about 794,234 (341)

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

On Some Transverse Geometrical Structures of Lifted Foliation to Its Conormal Bundle

The Scientific World Journal, 2015
We consider the lift of a foliation to its conormal bundle and some transverse geometrical structures associated with this foliation are studied. We introduce a good vertical connection on the conormal bundle and, moreover, if the conormal bundle is ...
Cristian Ida, Alexandru Oană
doaj   +1 more source

On Procesi bundles [PDF]

arXiv, 2013
Procesi bundles are certain vector bundles on symplectic resolutions of symplectic quotient singularities for wreath-products of the symmetric groups with Kleinian groups. Roughly speaking, we can define Procesi bundles as bundles on resolutions that provide derived McKay equivalence. In this paper we classify Procesi bundles on resolutions obtained by
arxiv  

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Temperature fields and heat transfer in free-packed fuel pin bundles cooled by heavy liquid metal

Nuclear Energy and Technology, 2016
The paper considers heat transfer and temperature fields in a free-packed fuel pin bundle cooled by a heavy liquid metal with different types of spacing.
A.V. Zhukov, Yu.A. Kuzina, A.P. Sorokin, V.V. Privezentsev   +3 more
doaj   +1 more source

Is Bundling Anticompetitive? [PDF]

, 2002
I analyze the implications of bundling on price competition in a market for complementary products. Using a model of imperfect competition with product differentiation, I identify the incentives to bundle for two types of demand functions and study how they change with the size of the bundle. With an inelastic demand, bundling creates an advantage over
openaire   +3 more sources

Bundle Gerbes

Journal of the London Mathematical Society, 1996
Just as $\Cstar$ principal bundles provide a geometric realisation of two-dimensional integral cohomology; gerbes or sheaves of groupoids, provide a geometric realisation of three dimensional integral cohomology through their Dixmier-Douady class. I consider an alternative, related, geometric realisation of three dimensional cohomology called a bundle ...
openaire   +3 more sources

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Improving Outcomes in Mechanically Ventilated Adult ICU Patients Following Implementation of the ICU Liberation (ABCDEF) Bundle Across a Large Healthcare System

Critical Care Explorations
OBJECTIVES:. To measure how the ICU Liberation Bundle (aka ABCDEF Bundle or the Bundle) affected clinical outcomes in mechanically ventilated (MV) adult ICU patients, as well as bundle sustainability and spread across a healthcare system. DESIGN:.
Juliana Barr, MD, FCCM, Brenda Downs, MSN, APRN, ACNS-BC, Ken Ferrell, MS-BMI, Mojdeh Talebian, MD, FCCP, Seth Robinson, MD, FCCP, Liesl Kolodisner, MHSA, CPA, Heather Kendall, RN, MSN, PHN, Janet Holdych, PharmD, CPHQ   +7 more
doaj   +1 more source

Semistability of Lazarsfeld-Mukai bundles via parabolic structures [PDF]

arXiv, 2017
Our aim in this article is to produce new examples of semistable Lazarsfeld- Mukai bundles on smooth projective surfaces $X$ using the notion of parabolic vector bundles. In particular, we associate natural parabolic structures to any rank two (dual) Lazarsfeld-Mukai bundle and study the parabolic stability of these parabolic bundles. We also show that
arxiv