Results 111 to 120 of about 817,701 (334)

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

Towards Understanding the Basis of Brucella Antigen–Antibody Specificity

open access: yesMolecules
Brucellosis continues to be a significant global zoonotic infection, with diagnosis largely relying on the detection of antibodies against the Brucella O-polysaccharide (O-PS) A and M antigens.
Amika Sood   +2 more
doaj   +1 more source

Temperature fields and heat transfer in free-packed fuel pin bundles cooled by heavy liquid metal

open access: yesNuclear Energy and Technology, 2016
The paper considers heat transfer and temperature fields in a free-packed fuel pin bundle cooled by a heavy liquid metal with different types of spacing.
A.V. Zhukov   +3 more
doaj   +1 more source

Regulatory Bundling

open access: yesSSRN Electronic Journal, 2018
Regulatory bundling consists of the ability of administrative agencies to aggregate and disaggregate rules. Agencies, in other words, can bundle what would otherwise be multiple rules into just one. Conversely, they can split one rule into several. This observation parallels other recent work on how agencies can aggregate adjudications and enforcement ...
Jennifer Nou   +2 more
openaire   +3 more sources

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Improving Outcomes in Mechanically Ventilated Adult ICU Patients Following Implementation of the ICU Liberation (ABCDEF) Bundle Across a Large Healthcare System

open access: yesCritical Care Explorations
OBJECTIVES:. To measure how the ICU Liberation Bundle (aka ABCDEF Bundle or the Bundle) affected clinical outcomes in mechanically ventilated (MV) adult ICU patients, as well as bundle sustainability and spread across a healthcare system. DESIGN:.
Juliana Barr, MD, FCCM   +7 more
doaj   +1 more source

On Some Transverse Geometrical Structures of Lifted Foliation to Its Conormal Bundle

open access: yesThe Scientific World Journal, 2015
We consider the lift of a foliation to its conormal bundle and some transverse geometrical structures associated with this foliation are studied. We introduce a good vertical connection on the conormal bundle and, moreover, if the conormal bundle is ...
Cristian Ida, Alexandru Oană
doaj   +1 more source

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