Results 221 to 230 of about 70,917 (350)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Challenges in AVNRT ablation in a patient with previous atrio-pulmonary Fontan surgery: a case report. [PDF]

Eur Heart J Case Rep
Jeewooth A, Kaushik A, Jaswal A, Chakravarty A.   +3 more
europepmc   +1 more source

Electrophysiological Characteristics and Mechanism of His‐Bundle Pacing Guided by Electrocardiograms in Uninterrupted Real‐Time Monitoring Technique [PDF]

Jinyan Zhong, Longfu Jiang, Y. Zhang, Nan Zheng, Hengdong Li   +4 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Conduction system pacing in a patient with persistent left superior vena cava and absent right superior vena cava: a case report. [PDF]

J Med Case Rep
Rodriguez-Queralto O, Gonzalez-Matos C, Zaraket F, Casteig B, Jimenez-Lopez J, Valles E.   +5 more
europepmc   +1 more source

Reply to the letter regarding the article ‘Predictors of the efficacy of His bundle pacing in patients with a prolonged PR interval: A stratified analysis of the HOPE‐HF randomized controlled trial’ [PDF]

Nandita Kaza, Zachary I. Whinnett, Daniel Keene   +2 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Left bundle branch pacing in patients with structural heart disease: personalizing cardiac resynchronization therapy. [PDF]

Europace
Joza J, Luermans J, Mardigyan V, Burri H, Jastrzębski M, Vijayaraman P, Vernooy K.   +6 more
europepmc   +1 more source

Mathematical analysis of the relationship between intra- and extracellular potentials from His bundle in rabbit heart

, 2009
Panli Tian
openalex   +1 more source

Complete heart block during permanent His bundle pacing: Is it a novel complication? [PDF]

Saad Ullah Malik, Pugazhendhi Vijayaraman   +1 more
openalex   +1 more source