Results 51 to 60 of about 575 (116)

Physical Fitness Dynamics Shape Immune Remodeling in Healthy Aging: A 3‐Year Longitudinal Study

Aging Cell, Volume 25, Issue 3, March 2026.
In a 3‐year longitudinal study of healthy older adults, intraindividual declines in physical fitness and strength were linked to dynamic immune remodeling, including shifts toward senescent and regulatory T cell phenotypes, despite stable activity levels.
Christopher Weyh, Vincent Größer, Luciele Guerra Minuzzi, Torsten Frech, Kristina Gebhardt, Svenja Nolte, Theresa Dombrowski, Manuela Andrea Hoffmann, Natascha Sommer, Robert Ringseis, Klaus Eder, Samuel Sossalla, Pascal Bauer, Karsten Krüger   +13 more
wiley   +1 more source

A Collaborative Approach to Pediatric Genetic Evaluation in the Era of Genomic Medicine

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 371-378, February 2026.
ABSTRACT To address the increased demand for genetic services and shortage of medical geneticists (MG), a collaborative pilot program was developed with a two‐part approach to care: (1) Initial genetic counselor (GC) appointment with exome sequencing (ES) and (2) follow‐up MG evaluation.
Sarah Jurgensmeyer Langas, Allison Goetsch Weisman, Valerie Allegretti, Katherine Kim, Roxanne Birriel, Carlos E. Prada   +5 more
wiley   +1 more source

When Heather needs her second mommy

Juvenile &Family Court Journal, Volume 76, Issue 4, Page 4-25, December 2025.
Abstract Obergefell v. Hodges, 576 U.S. 644 (2015) appeared to settle certain issues in family law by allowing same gender individuals to marry. Unfortunately, Obergefell left some areas of inequality between same gender and heterogeneous households, including visitation and family support rights and obligations, especially rights outside of and before
Daniel R. Fruit
wiley   +1 more source

CD4+ differentiated T regulatory cells is modified by physical fitness and visceral adipose tissue in young adults—A cross‐sectional study

Physiological Reports, Volume 13, Issue 16, August 2025.
High cardiorespiratory fitness and low visceral adiposity modulate CD4+ T regulatory cells. Fit participants shows be more responsible to mTORC1/2 inhibition via rapamycin or Torin‐1indicating a fitness‐ and adiposity‐dependent immunometabolic regulation.
Camila S. Padilha, Tiago Olean‐Oliveira, Caique Figueiredo, Vanessa R. Dos Santos, Gilson P. Dorneles, José Procópio Jabur Ribeiro, Rafael Deminice, Karsten Krüger, José C. Rosa‐Neto, Fábio S. Lira   +9 more
wiley   +1 more source

Strength in Numbers: How Social Resources Travel Together to Increase Employee Engagement

Asia Pacific Journal of Human Resources, Volume 63, Issue 2, April 2025.
ABSTRACT Based on a 2021 survey of 273 Australian workers across a range of occupations and industries, our structural equation modelling showed that workplace inclusion is a key driver of social resources for building employee engagement within the organisation.
Peter A. Murray, Kim Southey, Marnie Gibson, John Sands, Derek Ong   +4 more
wiley   +1 more source

Examining Roles, Challenges, and Opportunities Within the Metabolic Genetics Workforce

American Journal of Medical Genetics Part A, Volume 197, Issue 2, February 2025.
ABSTRACT The metabolic genetics clinic is a crucial hub for the management of patients with inborn errors of metabolism and other complex genetic conditions. Because more patients are being identified due to the expanded diagnostics, including newborn screening, and living longer with the advent of improved therapies, the multidisciplinary metabolic ...
Kara Simpson, Stephanie Offord, Chanel Suares, Jerry Vockley   +3 more
wiley   +1 more source

Pleistocene diversification of unifoliolate‐leaved Lupinus (Leguminosae: Papilionoideae) in Florida

Molecular Ecology, Volume 33, Issue 3, February 2024.
Abstract The importance and prevalence of recent ice‐age and post‐glacial speciation and species diversification during the Pleistocene across many organismal groups and physiographic settings are well established. However, the extent to which Pleistocene diversification can be attributed to climatic oscillations and their effects on distribution ...
Bruno Nevado, Guy W. Atchison, Edwin L. Bridges, Steve Orzell, Dmitry Filatov, Colin E. Hughes   +5 more
wiley   +1 more source

A Comprehensive Review of Free Radicals, Oxidative Stress, and Antioxidants: Overview, Clinical Applications, Global Perspectives, Future Directions, and Mechanisms of Antioxidant Activity of Flavonoid Compounds

Journal of Chemistry, Volume 2024, Issue 1, 2024.
Absorption​ of free radicals in the body cannot be done by antioxidant compounds originating from the human body, so exogenous antioxidants are required to help in their natural antioxidant action. Oxidative stress can be caused by an imbalance of free radical inhibitors and the accumulation of free radicals that enter cellular structures.
Sefren Geiner Tumilaar, Ari Hardianto, Hirofumi Dohi, Dikdik Kurnia, Mahmood Ahmed   +4 more
wiley   +1 more source

Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.

PLoS ONE, 2014
The high mortality rate from ovarian cancers can be attributed to late-stage diagnosis and lack of effective treatment. Despite enormous effort to develop better targeted therapies, platinum-based chemotherapy still remains the standard of care for ...
Ludmila Szabova, Sujata Bupp, Muhaymin Kamal, Deborah B Householder, Lidia Hernandez, Jerome J Schlomer, Maureen L Baran, Ming Yi, Robert M Stephens, Christina M Annunziata, Philip L Martin, Terry A Van Dyke, Zoe Weaver Ohler, Simone Difilippantonio   +13 more
doaj   +1 more source

Single-cell characterization of anterior segment development in the mouse reveals the cell types, pathways, and signals driving formation of the trabecular meshwork and Schlemm’s canal

eLife
Morphogenesis of the anterior segment (AS) is crucial for healthy ocular physiology and vision, but is only partially understood. The Schlemm’s canal (SC) and trabecular meshwork (TM) are essential drainage tissues within the AS, and their proper ...
Revathi Balasubramanian, Nicholas Tolman, Taibo Li, Abdul Hannan, Violet Bupp-Chickering, Karina Polanco, Aakriti Bhandari, Sally Zhou, Marina Simón, John Peregrin, Christa Montgomery, Krishnakumar Kizhatil, Jiang Qian, Simon WM John   +13 more
doaj   +1 more source