Results 161 to 170 of about 62,498 (301)

Astrocytic connexin43 phosphorylation contributes to seizure susceptibility after mild traumatic brain injury

The FEBS Journal, EarlyView.
Astrocytic gap junctions formed by connexin43 (Cx43) help maintain brain homeostasis. After mild traumatic brain injury (TBI), total cortical Cx43 increases and redistributes toward a soluble, non‐junctional pool with elevated hemichannel activity and increased phosphorylation at serine 368 (pCx43S368).
Carmen Muñoz‐Ballester, Owen Leitzel, Samantha Golf, Chelsea M. Phillips, Michael J. Zeitz, Rahul Pandit, Elizabeth Wash, Jenna V. Donohue, Elizabeth A. Istre, James W. Smyth, Samy Lamouille, Stefanie Robel   +11 more
wiley   +1 more source

High‐Fat Diet Reprograms the Periapical Immune Landscape in a Mouse Model of Apical Periodontitis: A Spatial Transcriptomics Study

International Endodontic Journal, EarlyView.
ABSTRACT Introduction Apical periodontitis (AP) is an inflammatory disease of the periapical tissues driven by host responses to endodontic infection, and systemic metabolic disturbances, such as high‐fat diet (HFD)–induced dysmetabolism, may exacerbate tissue destruction. This study aimed to determine how chronic HFD exposure alters periapical myeloid
Maryam Ghaffari, Aiman Ali, Clement Hartadi, Annie Shrestha   +3 more
wiley   +1 more source

Clinical Responses to Cocaine-Positive Urine Drug Screens in Patients Receiving Chronic Opioid Therapy: A Four-Patient Case Series. [PDF]

Orthop Rev (Pavia)
Hasoon J, Chuan J, Viswanath O, Urits I.
europepmc   +1 more source

Buprenorphine, an alternative treatment for opioid dependence /

, 1992
Shipping list no.: 92-0491-P."Based on the papers and discussions from a technical review on 'Buprenorphine: An Alternative Treatment for Opioid Dependence' held on March 16-17, 1989 in Rockville, MD."Includes bibliographical references.Buprenorphine ...
National Institute on Drug Abuse., Blaine, Jack D.   +1 more
core  

Stigmatising substance‐related language in the electronic health records of hospitalised patients after addiction consult service implementation

Internal Medicine Journal, EarlyView.
Abstract Objectives Stigmatising language about patients with substance use disorders (SUD) is common in healthcare settings and negatively impacts patient care. Addiction consult services are associated with improved clinician attitudes and less stigmatising views towards patients with SUD.
Ryder Cuppett, Justin Birge, Kristin Daniel, Alëna A. Balasanova   +3 more
wiley   +1 more source

Dosage and Administration-Related Emotional and Clinical Outcomes of Buprenorphine Treatment for Opioid Use Disorder: A Systematic Review and Meta-Analysis. [PDF]

Healthcare (Basel)
Xiao Y, Ramos MR, Montgomery-Marks P.
europepmc   +1 more source

Medical emergency response related to MedicAtion InciDents (MERRMAID): a case series and lessons to improve medication safety

Internal Medicine Journal, EarlyView.
Abstract Background Evidence suggests that some medical emergencies in hospital are associated with preventable medication errors or adverse reactions. Aim The purpose of this case series was to investigate and describe the proportion of Medical Emergency Response Team (MERT) activations that are medication‐related, the degree of preventability and ...
Ian Coombes, Amelia Anderson, Fiona Coombes, Gloria Wong, Daisy Lindsay, John Gowardman, Peter Donovan, Sinead Carmichael, Bianca Levkovich, Karen Davies   +9 more
wiley   +1 more source

Comparative Toxicological Profiling Reveals Divergent Redox, Mitochondrial, and Cellular Toxicity to Structurally Diverse Opioids. [PDF]

J Xenobiot
Pizent A, Zandona A, Jurič A, Tariba Lovaković B, Rašić D, Kopjar N, Vuković K, Katalinić M, Rešić A, Canjuga I, Vrdoljak AL, Karačonji IB.   +11 more
europepmc   +1 more source

Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Introduction Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep‐related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long‐term use. Despite these risks, Canada lacks standardized prescribing guidelines for older adults with
Anum Ali, Mina Tadrous, Chizaram Eje, Laleh Rashidian, Arrani Senthinathan, Cherry Chu, Kerry Kuluski, Sara J. T. Guilcher   +7 more
wiley   +1 more source

Buprenorphine initiation in fentanyl use: Practical strategies for family physicians. [PDF]

Can Fam Physician
Aboud H, Albert OM.
europepmc   +1 more source