Results 181 to 190 of about 62,498 (301)

Comparative efficacy of naltrexone-accelerated versus sublingual buprenorphine in opioid withdrawal management and initiating injectable naltrexone treatment: study protocol for a randomized controlled trial. [PDF]

Front Psychiatry
Jafari S, Rahimi-Movaghar A, Noroozi A, Malekifar P, Fotouhi A.   +4 more
europepmc   +1 more source

Targeting pepsin provides superior protection to acid suppression in reflux‐associated airway inflammation and lung dysfunction

Experimental Physiology, EarlyView.
Abstract Gastro‐oesophageal reflux disease is a prevalent condition associated with extra‐oesophageal manifestations, such as pulmonary inflammation. Pepsin, an essential gastric enzyme, has been implicated in pulmonary complications owing to its inflammatory effects.
Thiago Meneses Araújo Leite Sales, Humberto Barbosa da Costa Filho, Kalinne Kelly Lima Gadelha, Kerolayne de Melo Nogueira, Álvaro Xavier Franco, Carlos Eduardo da Silva Monteiro, Maria Klayre Araújo de Sousa, Monalisa Cássias Souza, Isabele de Sá Silveira Melo, Lucas Antonio Duarte Nicolau, Marco Antonio de Freitas Clementino, Pedro Jorge Caldas Magalhães, Alexandre Havt, Pedro Marcos Gomes Soares, Daniel Sifrim, Marcellus Henrique Loiola Ponte de Souza   +15 more
wiley   +1 more source

Exploratory evaluation of encapsulated kratom using multimodal quantitative sensory testing in dogs. [PDF]

Front Pharmacol
Maxwell EA, Hardison A, Moura RA, Grewal MK, Miscioscia EL, Perez-Rodriguez V, Hecker F, Portela DA, Bertran J, Gour A, McCurdy CR, Sharma A.   +11 more
europepmc   +1 more source

Exercise during 14 days of head down tilt bedrest attenuates motor unit impairments in older humans

Experimental Physiology, EarlyView.
Abstract Head‐down tilt bedrest (HDBR) models the effects of mechanical unloading on neuromuscular function. The efficacy of exercise in preserving motor unit (MU) function in older adults during HDBR remains unclear. This study investigated the effects of 14‐day HDBR on MU properties in older adults and the protective role of exercise.
Philippe St‐Martin, Jean‐Christophe Lagacé, Mathil Ruel, Ahmed Ghachem, Guillaume Léonard, Eleonor Riesco, Mathew Piasecki, Jamie S. McPhee, Isabelle J. Dionne   +8 more
wiley   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source

Same Drugs, Different Clinical Questions: Concurrent Combination Versus Sequential Add-On Therapy in Neuropathic Pain. [PDF]

Eur J Pain
Sokmen O.
europepmc   +1 more source

Running‐based rehabilitation does not improve muscle function after volumetric muscle loss despite improving hindlimb weight‐bearing asymmetry in mice

Experimental Physiology, EarlyView.
Abstract Volumetric muscle loss (VML) is a traumatic skeletal muscle injury characterized by chronic functional impairments in the affected muscle and adjacent uninjured bone. Rehabilitative strategies aimed at restoring limb function following VML, including voluntary running, have shown limited efficacy and in some cases have been detrimental.
Angela S. Bruzina, Molly R. Weberg, Ryan J. Willoughby, Gordon L. Warren, Jarrod A. Call, Sarah M. Greising   +5 more
wiley   +1 more source

Umbilical Cord Methadone and Buprenorphine Levels and Neonatal Opioid Withdrawal Severity.

JAMA Netw Open
Townsel C, Turner M, Biroon F, Broni E, Willimas SAS, Burd I, Kelly J.   +6 more
europepmc   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Opioid use disorder in custodial settings: Continuity of opioid agonist therapy at a critical clinical inflection point. [PDF]

Can Fam Physician
Albert OM, Arthur A, Beshara F.
europepmc   +1 more source