Results 211 to 220 of about 62,498 (301)

Medication transitions and predictors of illicit substance use during opioid agonist treatment: a three-year follow-up study. [PDF]

Addict Sci Clin Pract
Jobling N, Mjåland K, Clausen T, Heldal AT, Thylstrup B, Vederhus JK.   +5 more
europepmc   +1 more source

Signal detection and characterisation of a novel drug–drug interaction between methadone and a synthetic cannabinoid receptor agonist

British Journal of Pharmacology, Volume 183, Issue 23, Page 6787-6800, December 2026.
Background and Purpose Little is known about how synthetic cannabinoid receptor agonist (SCRA) co‐use with other psychoactive substances may exacerbate risk of death. This study aimed to characterise the polypharmacy of deaths where SCRAs were detected at post‐mortem, investigate the cardiotoxicity of SCRAs and probe their inhibition of human ether‐a ...
Kirsten L. Rock, Louise M. Hesketh, Hongwei Cheng, Shuoqi Chen, Simon Hudson, Graeme Henderson, Jules C. Hancox, Michael J. Shattock, Michael J. Curtis, Caroline S. Copeland   +9 more
wiley   +1 more source

Pharmacological Management of Opioid Use Disorder: A Systematic Review and Network Meta-Analysis: Prise en charge pharmacologique du trouble de l'usage des opiacés : revue systématique et méta-analyse en réseau. [PDF]

Can J Psychiatry
Rodrigues M, Dennis BB, Sadeghirad B, Oprea A, Malik M, Naji LN, McEvoy A, Malhotra D, Parpia S, Thabane L, Samaan Z.   +10 more
europepmc   +1 more source

Opioid Use and Family Members' Experiences of Opioids in Paediatric Cancer Pain Management: An Integrative Review

Scandinavian Journal of Caring Sciences, Volume 40, Issue 4, December 2026.
ABSTRACT Aim To analyse the use of opioids in children with cancer and the experiences of their family members regarding opioids used in pain management to improve family nursing. Design An integrative review. Methods A systematic literature search was carried out in four databases (CINAHL, MEDLINE, PsycInfo and Scopus) in August 2023, and was ...
Noora Puusa, Eeva Harju, Maija‐Liisa Kalliomäki, Elina Haavisto   +3 more
wiley   +1 more source

When Tapering Is Not an Option: Transitioning From High-Dose Methadone to Buprenorphine. [PDF]

Cureus
Petelinsek S, Morris J, Zaugg E, Coudreaut M.   +3 more
europepmc   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

An Antimicrobial, Cell‐Adhesive, and Growth Factor‐Producing Living Material Engineered From Bacillus subtilis Biofilms for Wound Healing

Advanced Healthcare Materials, Volume 15, Issue 41, 6 November 2026.
Bacillus subtilis is engineered to produce cell‐adhesive biofilms by functionalization of its biofilm scaffold protein TasA with a cell‐adhesion sequence. Living bacteria within the biofilm are also engineered to secrete growth factors and natively produce antimicrobial peptides (AMPs), resulting in a cell‐adhesive, antimicrobial, and growth factor ...
Mélanie Côté‐Cyr, Marie‐Jeanne Archambault, Caroline Dupuis, Steve Bourgault   +3 more
wiley   +1 more source

Impact of a National Stepped-Care Model of Opioid Use Disorder Treatment on Access to Medication Therapies Among Homeless-Experienced Veterans. [PDF]

Health Serv Res
Li H, Baylis JD, Huebler S, Gordon AJ, Hawkins E, Hagedorn HJ, Kertesz SG, Suo Y, Zhang Y, Jones AL.   +9 more
europepmc   +1 more source

Ixodes ricinus‐Contact Phase Inhibitor Promotes Functional Recovery and Attenuates Neutrophil Associated Neuroinflammation After Experimental Intracerebral Hemorrhage

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Ixodes ricinus‐Contact Phase Inhibitor (Ir‐CPI), a selective FXIa/XIIa inhibitor with reported thromboinflammatory modulatory properties, improves recovery after intracerebral hemorrhage (ICH) without increasing bleeding. By targeting thromboinflammation, Ir‐CPI limits neutrophil infiltration and NET formation, reducing secondary neuronal injury. These
Stéphanie Demoulin, Annelise Letourneur, Florent Lebrun, Nicolas Violle, Denis Vivien, Valérie Pireaux   +5 more
wiley   +1 more source