Results 251 to 260 of about 42,523 (291)
Astroglial CB1 Reveal Sex‐Specific Synaptic Effects of Amphetamine
Main Points Astroglial CB1 mediate long‐term depression in the NAc through purine release. Amphetamine occludes LTD in male mice by inducing the saturation of A1 receptors. Astroglial CB1 mediate behavioral amphetamine effects in males, but not in females.
Yamuna Mariani+15 more
wiley +1 more source
ABSTRACT Background Patients with sickle cell disease (SCD) experience painful vaso‐occlusive episodes that increase with age; a subset develops chronic pain (CP). CP is usually managed with acute pain management guidelines despite evidence of ineffectiveness.
Ashwin Patel+6 more
wiley +1 more source
ABSTRACT Background Seizures after the use of cannabinoids are reported, but no precise descriptions of the characteristics of subjects and factors that may trigger seizures are available. Objectives To study the characteristics and circumstances associated with the occurrence of seizures in individuals using cannabinoids for medical or recreational ...
Marie‐Laure Laroche+4 more
wiley +1 more source
ABSTRACT Background Long‐term opioid treatment (L‐TOT) may have consequences that are mediated by factors affecting functionality and health‐related quality of life. This study aimed at investigating associations between L‐TOT and clinical outcomes including sustained attention, short‐term and working memory, worst pain intensity, sleep quality, mood ...
Dalia Abou‐Kassem+5 more
wiley +1 more source
ABSTRACT Background Given the impact of chronic pain on cognition, CRPS may affect specific cognitive functions. However, cognitive functioning is rarely assessed in CRPS, and previous studies have examined only limited domains. As a result, it remains unclear which cognitive functions are affected and whether impairments are CRPS‐specific.
Corinne van den Berg+3 more
wiley +1 more source
Responding to reports of nitazene toxicity in Australia
Medical Journal of Australia, Volume 222, Issue 5, Page 216-219, March 2025.
Brendan Clifford+5 more
wiley +1 more source
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The effects of buprenorphine in buprenorphine-maintained volunteers
Psychopharmacology, 1997Buprenorphine is a mu opioid partial agonist currently used as an analgesic, and being developed for the treatment of opioid dependence. The purpose of this study was to determine the abuse liability of parenteral buprenorphine in volunteers maintained on daily sublingual (SL) buprenorphine (8 mg).
Eric C. Strain+4 more
openaire +3 more sources
The radioimmunoassay of buprenorphine
European Journal of Clinical Pharmacology, 1980Antisera to buprenorphine were obtained in rabbits immunised with 3-0-carboxymethylbuprenorphine and N-hemisuccinyl-norbuprenorphine conjugated to bovine serum albumin. Using the latter antiserum and tritium labelled buprenorphine a radioimmunoassay have good accuracy and precision was developed for concentrations as low as 50 picograms in 1 ml of ...
M. R. D. Bennett+6 more
openaire +3 more sources