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Bupropion overdose in an adolescent

Pediatric Emergency Care, 2001
Bupropion is a relatively new monocyclic antidepressant whose mechanism of action remains unknown. In addition to its use as an antidepressant, it has also been suggested to be effective in children with attention deficit hyperactive disorder and more recently as an aid in the cessation of cigarette smoking.
Sara Ayers, Joseph D. Tobias
openaire   +3 more sources

Bupropion-induced angioedema

American Journal of Health-System Pharmacy, 2008
A case of angioedema caused by bupropion used for smoking cessation is discussed.A 33-year-old man with a 12-pack-year of smoking history developed a rash on his extremities 18 days after the initiation of bupropion, followed by pruritus and swelling of the arms, feet, lower lip, and tongue by day 20.
Amy E. Tackett, Kelly M. Smith
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Bupropion, is it Here to Stay?

DICP, 1989
Evaluation of the antidepressant efficacy of bupropion.
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Intentional bupropion overdoses

The Journal of Emergency Medicine, 2004
Bupropion is an antidepressant that has recently seen increased usage in smoking cessation. This increased usage, along with its potential for causing seizures, has renewed interest among clinicians about the effects of this drug. The purpose of this study is to describe the clinical course of intentional bupropion overdoses in adults and adolescents ...
Daniel C. Keyes   +2 more
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Bupropion overdose and seizure

The American Journal of Emergency Medicine, 1994
There is little experience with overdose of the relatively new antidepressant bupropion. The case of an 18-year-old healthy adult female patient after an intentional ingestion of 9 g of bupropion is presented. Her hospital course was significant for grand mal seizures, sinus tachycardia without conduction abnormality, and complete neurological recovery.
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Bupropion for Depression in Schizophrenia

Clinical Neuropharmacology, 2010
The catecholaminergic theory of depression assumes dysfunctional neurotransmission of dopamine and norepinephrine. Therefore, the antidepressant bupropion, a dual dopamine and norepinephrine reuptake inhibitor, might be a valuable treatment option also in schizophrenic patients with major depressive episodes.
Andrea Eer   +3 more
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Bupropion‐induced somnambulism

Addiction Biology, 2003
AbstractWhereas there are some case reports of bupropion‐induced vivid dreaming and nightmares, until now it has not been associated with somnambulism. A case is reported of a patient treated with bupropion as a smoking cessation medication, who developed somnambulism during nicotine withdrawal.
Yasser Khazaal   +2 more
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The aqueous stability of bupropion

Journal of Pharmaceutical and Biomedical Analysis, 2010
In this study the aqueous stability of bupropion was determined and the pH-degradation profile was obtained. The effects of hydrogen ion, solvent and hydroxide ion concentration are discussed with particular emphasis on the kinetics of degradation of bupropion.
John F. Gilmer   +3 more
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Bupropion Is a Nicotinic Antagonist

The Journal of Pharmacology and Experimental Therapeutics, 2000
Neuronal nicotinic receptors are ligand-gated ion channels of the central and peripheral central nervous system that regulate synaptic activity from both pre- and postsynaptic sites. The present study establishes the acute interaction of bupropion, an antidepressant agent that is also effective in nicotine dependence, with nicotine and nicotinic ...
J E, Slemmer, B R, Martin, M I, Damaj
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▼Naltrexone/bupropion for obesity

Drug and Therapeutics Bulletin, 2017
▼ Naltrexone/bupropion (Mysimba - Orexigen Therapeutics Ireland Limited) is a fixed-dose combination product for the treatment of adults who are obese or overweight with at least one weight-related comorbidity, as an adjunct to diet and lifestyle modifications.
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