Results 161 to 170 of about 40,708 (270)

Systematic Review: Efficacy, Safety and Metabolic Outcomes of GLP‐1 Receptor Agonists in Inflammatory Bowel Disease

open access: yesAlimentary Pharmacology &Therapeutics, Volume 63, Issue 1, Page 17-39, January 2026.
GLP‐1 receptor agonists are generally effective in weight loss and improvement in metabolic markers. They are well tolerated in patients with inflammatory bowel disease, with observational evidence showing no increased risk of disease exacerbation and possible signals of reduced steroid use, hospitalization, and surgery. ABSTRACT Background Obesity and
Brooke Maracle   +8 more
wiley   +1 more source

Weight‐reducing treatments are associated with an improvement in depression, functional health status, and quality of life: A meta‐analysis of randomized controlled trials

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 347-357, January 2026.
Abstract Aim To assess whether there is a beneficial or detrimental effect of weight reduction on mental health. Materials and methods Meta‐analysis of randomized trials performed for weight loss, in which weight loss at endpoint was greater than 5% in the intervention arm and smaller than 5% in the control arm, obtained with any surgical, endoscopic ...
Giovanni Antonio Silverii   +9 more
wiley   +1 more source

Efficacy and safety of European Medicines Agency (EMA)‐approved pharmacological, endoscopic, and surgical treatments in different classes of obesity: A network meta‐analysis of randomised controlled trials for the development of the SIO (Società Italiana Obesità) Italian guidelines for the diagnosis and treatment of overweight and obesity

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 358-378, January 2026.
Abstract Aims We aimed at comparing different approved strategies (obesity management medications—OMM, endoscopic bariatric procedures—EBP, and metabolic bariatric surgery—MBS) with lifestyle intervention/placebo/no therapy (LSI/Pbo/NT) for the treatment of different BMI‐based classes of obesity (i.e., overweight—BMI: 25–29.9 kg/m2; class I—BMI: 30–34 ...
Rocco Barazzoni   +10 more
wiley   +1 more source

Improved health‐related quality of life with tirzepatide versus semaglutide in adults with obesity or overweight from the SURMOUNT‐5 trial

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 452-462, January 2026.
Abstract Aims In SURMOUNT‐5, tirzepatide led to greater body weight (BW) reduction versus semaglutide in adults with obesity without T2D. Health‐related quality of life (HRQoL) with tirzepatide versus semaglutide in SURMOUNT‐5 was evaluated. Materials and Methods This analysis included on‐treatment data from participants who received ≥1 dose of ...
Alpana P. Shukla   +5 more
wiley   +1 more source

Food and the brain: Neural and endocrine control of feeding, metabolism, and reproduction

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Feeding and reproductive function are regulated by intricate systems that monitor food availability and energy stores, and on the basis of energy status, promote or put a brake on reproduction. This is particularly evident in the systems that regulate feeding and reproductive state in female mammals.
Naira da Silva Mansano   +2 more
wiley   +1 more source

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