Naltrexone/Bupropion, Liraglutide, or Semaglutide as Adjuvant Therapy After Metabolic and Bariatric Surgery: An Observational Study. [PDF]
Obes Sci PractABSTRACT Introduction Obesity is a chronic and relapsing disease and metabolic and bariatric surgery (MBS) provides the greatest weight loss efficacy to improve obesity related complications. However, weight recurrence and suboptimal weight loss occur in some patients leading to a recurrence of disease.
Brancatisano A, Ryan B.
europepmc +2 more sources
“Ghost tablet” husks excreted in feces in large bupropion XL overdose [PDF]
, 2018 Background: Extended-release medications are widely prescribed across the spectrum of medical specialties; however, there is heterogeneity in how they are formulated.
Nanagas, Kristine +2 more
core +1 more source
Integration of Tobacco Treatment Services into Cancer Care at Stanford. [PDF]
, 2020 As part of a National Cancer Institute Moonshot P30 Supplement, the Stanford Cancer Center piloted and integrated tobacco treatment into cancer care. This quality improvement (QI) project reports on the process from initial pilot to adoption within 14 ...
Fielding-Singh, Priya +7 more
core +2 more sources
A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug response [PDF]
, 2008 The pregnane X receptor (PXR) and the constitutive androstane receptor (CAR) are closely related orphan nuclear hormone receptors that play a critical role as xenobiotic sensors in mammals.
Anja Rode +19 more
core +4 more sources
British Journal of Clinical Pharmacology, 2020 AIMS To compare the benefits and harms of naltrexone-bupropion using evidence from clinical study reports (CSRs). METHODS We searched FDA and EMA websites, PubMed, and Clinicaltrials.gov (May 2016) to identify pivotal trials; we then sent a freedom of ...
I. Onakpoya +4 more
semanticscholar +1 more source
Enhanced neural response to anticipation, effort and consummation of reward and aversion during Bupropion treatment [PDF]
, 2016 Background We have previously shown that the selective serotonergic re-uptake inhibitor, citalopram, reduces the neural response to reward and aversion in healthy volunteers. We suggest that this inhibitory effect might underlie the emotional blunting
C. McCabe +5 more
core +1 more source
Bupropion for the Treatment of Apathy in Alzheimer Disease
JAMA Network Open, 2020 Key Points Question Is bupropion an effective and safe treatment for apathy in nondepressed patients with dementia of Alzheimer type? Findings In this 12-week, multicenter, double-blind, placebo-controlled, randomized clinical trial, 54 patients received
F. Maier +23 more
semanticscholar +1 more source
Pharmacology of novel psychoactive substances [PDF]
, 2016 This PhD work consists of an in vitro and in vivo part. In the in vivo part, we investigated the role of dopamine in the acute clinical effects of 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) in healthy human subjects.
Rickli, Anna
core +1 more source
Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg depression rating scale, the gold standard clinician rating scale : a meta-analysis of randomised placebo-controlled trials [PDF]
, 2020 It has been claimed that efficacy estimates based on the Hamilton Depression Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the instrument's poor psychometric properties.
Hengartner, Michael Pascal +3 more
core +2 more sources
Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS [PDF]
, 2016 Bupropion metabolites formed via oxidation and reduction exhibit pharmacological activity, but little is known regarding their stereoselective disposition.
Desta, Zeruesenay +3 more
core +1 more source