Efficacy of new-generation antidepressants assessed with the Montgomery-Asberg depression rating scale, the gold standard clinician rating scale : a meta-analysis of randomised placebo-controlled trials [PDF]
It has been claimed that efficacy estimates based on the Hamilton Depression Rating-Scale (HDRS) underestimate antidepressants true treatment effects due to the instrument's poor psychometric properties.
Hengartner, Michael Pascal +3 more
core +2 more sources
Bu çalışmada, farelerde desipramin, venlafaksin ve bupropiyonun depresyon ve anksiyete üzerine etkilerini araştırmayı amaçladık. Klasik trisiklik antidepresan, desipramin, serotonin-norepinefrin geri alım inhibitörü venlafaksin ve ikinci jenerasyon ...
Mehmet Emin Büyükokuroğlu +6 more
doaj +1 more source
Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial [PDF]
Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and ...
Bamidis, Panagiotis D. +10 more
core +3 more sources
Galactorrhoea as a side effect due to Bupropion- a case report
Introduction Bupropion is a NDRI antidepressant with action on both serotonin and nicotinic receptors. Endocrine and sexual adverse effects are very rare and hence very unlikely to cause hyperprolactinemia.
D. Bhandutia, S. Nayok
doaj +1 more source
The effectiveness, safety and cost-effectiveness of cytisine versus varenicline for smoking cessation in an Australian population: a study protocol for a randomized controlled non-inferiority trial [PDF]
Smoking cessation medications are effective but often underutilised because of costs and side effects. Cytisine is a plant-based smoking cessation medication with over 50 years of use in Central and Eastern Europe.
Boland, Veronica C. +19 more
core +1 more source
The potential of inhibitory metabolites of perpetrator drugs to contribute to drug-drug interactions (DDIs) is uncommon and underestimated. However, the occurrence of unexpected DDI suggests the potential contribution of metabolites to the observed DDI ...
Caifu Xue, Xunjie Zhang, Weimin Cai
doaj +1 more source
Background Pharmacodynamics and pharmacogenetics are being explored in pharmacological treatment response for major depressive disorder (MDD). Interactions between genotype and treatment response may be dose dependent.
Jay Fawver +4 more
doaj +1 more source
Peptic Ulcer Disease Following Use of Bupropion: A Case Report
Background: Bupropion is a dopamine reuptake inhibitor, which is prescribed as an effective drug for the treatment of depression and as a complementary drug for smoking cessation in more than 50 countries.
Zahra Momayez Sanat +2 more
doaj +1 more source
European Guidelines for Obesity Management in Adults [PDF]
Obesity is a chronic metabolic disease characterised by an increase of body fat stores. It is a gateway to ill health, and it has become one of the leading causes of disability and death, affecting not only adults but also children and adolescents ...
Busetto, Luca +6 more
core +2 more sources
Bupropion perceived as a stimulant by two patients with a previous history of cocaine misuse
BACKGROUND AND OBJECTIVE: Despite animal studies having shown a generalisation of the bupropion cue to cocaine, this drug has been used in cocaine abuse with mixed results. We here aimed at describing two cases which contradict current knowledge.
Alessandro E. Vento +6 more
doaj +1 more source

