Results 1 to 10 of about 4,696 (123)

Efficacy of bupropion and cognitive behavioral therapy in the treatment of methamphetamine use disorder: a systematic review and meta-analysis [PDF]

open access: yesBrazilian Journal of Psychiatry, 2023
Objectives: We assessed the efficacy of cognitive behavioral therapy and bupropion compared to cognitive behavioral therapy alone for methamphetamine use disorder. Methods: The selection criteria for this systematic review study with meta-analysis were
Luis Fernando Maya Apuy   +2 more
doaj   +1 more source

Adjunctive antidepressive pharmacotherapy in schizophrenia patients

open access: yesEuropean Psychiatry, 2021
Depressive symptoms during long-term course of schizophrenia constitute an important and frequent clinical problem. They may occur either as stand-alone major depressive episodes (MDEs) or as part of the schizophrenic negative syndrome.
M. Zink
doaj   +1 more source

Anxiolytic and antidepressant effect of zinc on rats and its impact on general behavioural parameters [PDF]

open access: yesVojnosanitetski Pregled, 2013
Background/Aim. Zinc is an essential element which has considerable interaction with gamma-aminobutyric acid A type receptors (GABAA) and glutamate receptors in the central nervous system (CNS).
Samardžić Janko   +8 more
doaj   +1 more source

Research on the Development of Theme Trends and Changes of Knowledge Structures of Drug Therapy Studies on Major Depressive Disorder Since the 21st Century: A Bibliometric Analysis

open access: yesFrontiers in Psychiatry, 2020
BackgroundAntidepressant treatment is one of the most effective ways of relieving or curing depressive symptoms in patients with major depressive disorder (MDD).
Li Duan   +7 more
doaj   +1 more source

Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor [PDF]

open access: yes, 2020
In the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR).
Belelli, Delia   +3 more
core   +1 more source

Network reconstruction of platelet metabolism identifies metabolic signature for aspirin resistance. [PDF]

open access: yes, 2014
Recently there has not been a systematic, objective assessment of the metabolic capabilities of the human platelet. A manually curated, functionally tested, and validated biochemical reaction network of platelet metabolism, iAT-PLT-636, was reconstructed
Bordbar, Aarash   +4 more
core   +2 more sources

Antidepressant drugs and the response in the placebo group: the real problem lies in our understanding of the issue [PDF]

open access: yes, 2012
In a recent paper, Horder and colleagues (Horder et al., 2010, J Psychopharmacol 25: 1277–1288) have suggested that the mainproblem in the Kirsch analysis is methodological. We argue that the results are similar irrespective of the method used.
Bech P   +8 more
core   +1 more source

Clinical relevance and treatment possibilities of bipolar rapid cycling [PDF]

open access: yes, 2002
Bipolar rapid cycling (RC) is defined as 4 or more affective episodes within 1 year. It has been postulated that RC is related to a poor response to lithium, to the same extent as mixed episodes or other atypical symptoms of the illness.
Amann, B.   +3 more
core   +1 more source

Management of bipolar depression

open access: yesIndian Journal of Psychological Medicine, 2011
Patients with bipolar disorder spend more time in a depressed than manic state, even with individualized treatment. To date, bipolar depression is often misdiagnosed and ineffectively managed both for acute episodes and residual symptoms.
Jae Seung Chang, Kyooseob Ha
doaj   +1 more source

Smoking and antidepressants pharmacokinetics: a systematic review [PDF]

open access: yes, 2017
Despite an increasingly recognized relationship between depression and smoking, little is known about how smoking influences antidepressant response and treatment outcomes.
Donato, H   +3 more
core   +1 more source

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