Results 31 to 40 of about 10,073,743 (132)

High Prevalence of Psychological Symptoms, Sexual Dysfunction, and Prolonged Medical Leave Two Years After Acute Leukemia Diagnosis—Patient Reported Outcome in Sweden

open access: yeseJHaem, Volume 6, Issue 5, October 2025.
ABSTRACT Introduction With the purpose of identifying unmet needs of patients with acute leukemia, survivors were identified from the Swedish National Acute Leukemia registries. Methods At six months and at two years from diagnosis, patients were requested by mail to report outcome with focus on depression, sick leave, and sexual dysfunction.
Emma Bergfelt Lennmyr   +5 more
wiley   +1 more source

Lithium Augmentation in Treatment‐Resistant Depression: A Qualitative Review of the Literature

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 688-701, October 2025.
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Angela Acero‐González   +8 more
wiley   +1 more source

Iconic Fictions: Narrating Recent Argentine History in Post-2000 Second-Generation Films [PDF]

open access: yes, 2012
Please note that this is an author-produced PDF of an article accepted for publication following peer review. The publisher version is available at:http://dx.doi.org/10.1386/shci.8.2.175_1.This article examines a recent trend in Argentine post ...
Garibotto, Verónica
core   +1 more source

The Global Landscape of Neuropsychiatric Prescribing Practices of Nurses: A Scoping Review

open access: yesInternational Journal of Mental Health Nursing, Volume 34, Issue 4, July 2025.
ABSTRACT Mental healthcare service access in South Africa is currently strained due to, among others, shortages of specialised mental healthcare professionals. The National Strategic Plan for HIV, TB and STIs (2023‐2028) recommends enabling nurses to diagnose, prescribe and dispense neuropsychiatric medication for promoting mental health services.
M. Naidoo, C. J. Filmalter, W. Cordier
wiley   +1 more source

The Blue Light‐Responsive Lateral Pathway of the Retinohypothalamic Tract Promotes Endocannabinoid‐Driven Modulation of Orexin Neurons

open access: yesJournal of Neurochemistry, Volume 169, Issue 6, June 2025.
Blue light stimulation of ipRGCs leads to endocannabinoid‐mediated modulation of orexin neuron activity via the retinohypothalamic network. (1) In the first step, blue light‐induced glutamate release from VGluT1/CB1‐positive input depolarizes the OX‐A neuron (red) in the PFH; (2) This depolarization triggers the biosynthesis and release of 2‐AG (green ...
Nicola Forte   +7 more
wiley   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

open access: yesMedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes   +4 more
wiley   +1 more source

Second-Harmonic-Generation-Active Oxyhalides: CuSb2O3X (X = Cl, Br)

open access: yes, 2021
Metal oxyhalides have attracted broad interest recently because of their diverse structures and versatile properties. Here, two oxyhalides, CuSb2O3Cl (1) and CuSb2O3Br (2), were studied by focusing on their nonlinear-optical properties.
Mei Yang (51996)   +7 more
core   +1 more source

Perillaldehyde Improves Parkinson‐Like Deficits by Targeting G3BP Mediated Stress Granule Assembly in Preclinical Models

open access: yesAdvanced Science, Volume 12, Issue 14, April 10, 2025.
This study uncovers that stress granules (SGs) are involved in the pathogenesis of Parkinson's disease (PD). Perillaldehyde (PAE) can improve Parkinson‐like deficits in preclinical models by directly binding to G3BP and instigating liquid–liquid phase separation (LLPS) of G3BP.
Minglv Fang   +12 more
wiley   +1 more source

Pharmacological Treatment of Neuropsychiatric Symptoms in Huntington's Disease: A Systematic Review

open access: yesMovement Disorders Clinical Practice, Volume 12, Issue 4, Page 418-431, April 2025.
ABSTRACT Background Studies focusing on the treatment of neuropsychiatric symptoms (NPS) in Huntington's disease (HD) are scarce and show a wide variation in design, outcome measures and methodological quality. The effectiveness of pharmacological treatment of NPS in HD has not been systematically reviewed so far.
Ruben L. Andriessen   +5 more
wiley   +1 more source

Mirtazapine versus other antidepressive agents for depression.

open access: yes, 2011
BACKGROUND: Mirtazapine has a unique mechanism of antidepressive action and is one of the commonly used antidepressants in clinical practice. OBJECTIVES: The aim of the present review was to assess the evidence on the efficacy and acceptability of ...
Churchill, R   +25 more
core   +1 more source

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