Results 11 to 20 of about 3,329 (118)

Overstated association between adolescent physical fitness and adulthood depression risk due to familial factors. [PDF]

open access: yesJ Intern Med
Abstract Objective Examine the association between adolescent cardiorespiratory fitness and future risk of depression and dispensation of antidepressants, including the role of familial confounding. Methods A cohort study with sibling‐comparisons based on Swedish men who participated in mandatory military conscription examinations from 1972 to 1995 ...
Ballin M   +4 more
europepmc   +2 more sources

Lithium Augmentation in Treatment-Resistant Depression: A Qualitative Review of the Literature. [PDF]

open access: yesPharmacotherapy
ABSTRACT Depression is the leading cause of disability worldwide, affecting people of all ages. Both pharmacological and non‐pharmacological therapies are available for its treatment. However, some patients do not respond to first‐line pharmacological interventions, referred to as treatment‐resistant depression (TRD).
Acero-González A   +8 more
europepmc   +2 more sources

Evaluation of Potential Hormonal Activities of Ashwagandha (Withania somnifera)

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Ashwagandha is a widely used herb in traditional medicine systems, particularly Ayurveda. Despite its extensive tradition, growing concerns regarding its potential endocrinological effects have prompted scientific scrutiny. This review systematically evaluates the current preclinical, clinical, and case study evidence concerning AS's effects ...
Günter Vollmer, Thomas Brendler
wiley   +1 more source

Antidepressivos de nova geração na neuropatia diabética dolorosa

open access: yes, 2011
The incidence of diabetic neuropathy increases with the duration of diabetes and the degree of hyperglycaemia. Pain is one of the most common and incapacitating symptoms of diabetic neuropathy and its pharmacological control is complex. The effectiveness
Gutiérrez-Álvarez, Ángela M.   +1 more
core   +2 more sources

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

Scopolamine as an Antidepressant: A Systematic Review

open access: yes, 2013
OBJECTIVES: The cholinergic-adrenergic hypothesis of mania and depression states that depression is characterized by an increase in central cholinergic activity relative to noradrenergic tone.
Jaffe, Robert J   +2 more
core   +1 more source

Trends in age‐sex‐specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2049-2062, July 2026.
Differences in antidepressant dispensation across the Nordic countries have been reported, but existing reviews are based on older data. We conducted a systematic review of population‐based studies reporting prevalence and/or incidence of antidepressant dispensation in the Nordic countries.
Marcel Ballin   +5 more
wiley   +1 more source

Antidepressivos de nova geração na neuropatia diabética dolorosa [PDF]

open access: yes, 2014
La incidencia de neuropatía diabética aumenta con la duración de la diabetes y el grado de hiperglicemia. El dolor es uno de los síntomas más comunes e incapacitantes de la neuropatía diabética y su control farmacológico es complejo.
Moreno, Carlos B.   +1 more
core   +1 more source

Antidepressant-induced analgesia in chronic non-malignant pain: A meta-analysis of 39 placebo-controlled studies

open access: yes, 1992
For 39 controlled studies on the analgesic effect of antidepressants, a meta-analysis was conducted to get an estimation of the effect size, and to obtain a sight on the possible modes of action and the methodology used.
Onghena, Patrick   +1 more
core   +1 more source

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 696-702, March 2026.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali   +4 more
wiley   +1 more source

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